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Why I’m Digging Deep Into Alzheimer’s

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Re: Why I’m Digging Deep Into Alzheimer’s

#81

Post by exelius »

mrfusion wrote: post #78
louprado wrote: post #76

The documentary "Under our Skin" details Alan MacDonald's breakthrough research on how Lyme disease causes Alzheimers. The 4 minute trailer is worth a watch[1], but basically Lyme disease is found in 7 or 10 brains of Alzheimers patients (small sample set). The Lyme disease spirochete literally drills countless pathways in the brain and that causes slow dementia. That spirochete also creates a biofilm which makes it…

But isn’t Lyme disease just in the eastern us? How would 70% of worldwide alz sufferers acquire it?

Good question!

That’s why we need research. We don’t know if they have a common cause or just a common mechanism of action. They very well could be the same disease; Lyme Disease is not well understood and has been implicated in all sorts of neurological diseases such as Multiple Sclerosis and Alzheimer’s.

But the link isn’t quite obvious enough and the potential treatments, which rules out government money; and aren’t considered to be profitable, which rules out commercial money. Good for Gates stepping in here

Re: Why I’m Digging Deep Into Alzheimer’s

#82

Post by DanBC »

bflesch wrote: post #20

It's great to see more investment into this disease. When my grandma fought Alzheimer's over the span of a decade it was very striking to see that the effect of a lack of hydration and the disease itself kind of overlapped. When she had a particularly bad day we used to give her a saline IV and you could immediately notice how she cleared up and regained her brain powers after each IV. I'm not up to date on current r…

> I'm not up to date on current research into that direction, but I think hydration plays a very big role in Alzeimer's symptoms on the elderly.

Here's some recent research you might be interested in:

https://www.nutraingredients.com/Article/2017/10/31/Major-EU...

Re: Why I’m Digging Deep Into Alzheimer’s

#83

Post by judah »

Michael Fossel and his biopharmaceutical company Telocyte claim[0] to have a novel, effective treatment for Alzheimers, one that does not simply target the amyloid and tau pathways. Telocyte's treatment is based on telomerase gene therapy, and is currently undergoing FDA safety trials.

According to Fossel, their telomerase gene therapy reverses cognitive decline in animal models, and they're confident the same will apply to humans. Human trials begin in 2018.

I wonder whether Gates has seen Telocyte's work.

[0]: http://www.michaelfossel.com/blog/?p=249

Re: Why I’m Digging Deep Into Alzheimer’s

#84

Post by JamesBarney »

Filligree wrote: post #12
maxst wrote: post #5

>Most of the major pharmaceutical companies continue to pursue the amyloid and tau pathways. Dementia Discovery Fund complements their work by supporting startups as they explore less mainstream approaches to treating dementia. That's very encouraging. Because what if it's something else?

The amyloid and tau pathways are our best hope of finding a simple solution, something we can reasonably fix with drugs. If it's something else, then chances are good it'll be far harder to fix, perhaps even requiring genetic engineering or medical nanotechnology. Finding out is still valuable, of course...

Why do you think this? Why couldn't it be as simple as stimulating glial cells?

Re: Why I’m Digging Deep Into Alzheimer’s

#85

Post by astura »

bitL wrote: post #48

FYI, taking sauna 4x a week seems to lower the risk of developing Alzheimer significantly (at least in Finland). I can also observe myself that taking hot phase 4-5x for 10-15 minutes followed by 2 minutes cold immersion every time in roughly 1.5 hours clears my brain/senses. Maybe the sweating helps overloaded brain drainage as well? I think Bezos must be applying some of these hacks on himself; he got recently in s…

"Liver spots" have noting to do with the liver.

Re: Why I’m Digging Deep Into Alzheimer’s

#86

Post by mrfusion »

exelius wrote: post #81
mrfusion wrote: post #78

Earlier quoted context omitted.

But isn’t Lyme disease just in the eastern us? How would 70% of worldwide alz sufferers acquire it?

Good question! That’s why we need research. We don’t know if they have a common cause or just a common mechanism of action. They very well could be the same disease; Lyme Disease is not well understood and has been implicated in all sorts of neurological diseases such as Multiple Sclerosis and Alzheimer’s. But the link isn’t quite obvious enough and the potential treatments, which rules out government money; and aren…

Thanks. I’m still not understanding how so many people could acquire Lyme disease and not have any of the other symptoms.

Re: Why I’m Digging Deep Into Alzheimer’s

#87

Post by kuwze »

louprado wrote: post #76

The documentary "Under our Skin" details Alan MacDonald's breakthrough research on how Lyme disease causes Alzheimers. The 4 minute trailer is worth a watch[1], but basically Lyme disease is found in 7 or 10 brains of Alzheimers patients (small sample set). The Lyme disease spirochete literally drills countless pathways in the brain and that causes slow dementia. That spirochete also creates a biofilm which makes it…

Although I have no clue how the body absorbs it, it seems that stevia (the alternative sweetener known as truvia) is remarkably good at curing lyme in vitro vs antibiotics[0].

[0]: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4681354/

Re: Why I’m Digging Deep Into Alzheimer’s

#88

Post by madshiva »

Chris2048 wrote: post #30
madshiva wrote: post #23

no need to have Alzheimer to see these poor old guy / women that can't do anything. We should die sooner, waste less resource and enjoy more.

What would you suggest?

Don't extend life...we discovered these things because we are older and older. I don't think that the solution is getting older. Don't know why I'm always getting down vote too. Life and his mystery.

Re: Why I’m Digging Deep Into Alzheimer’s

#89

Post by belenos46 »

mrfusion wrote: post #86
exelius wrote: post #81

Earlier quoted context omitted.

Good question! That’s why we need research. We don’t know if they have a common cause or just a common mechanism of action. They very well could be the same disease; Lyme Disease is not well understood and has been implicated in all sorts of neurological diseases such as Multiple Sclerosis and Alzheimer’s. But the link isn’t quite obvious enough and the potential treatments, which rules out government money; and aren…

Thanks. I’m still not understanding how so many people could acquire Lyme disease and not have any of the other symptoms.

Because Lyme is often asymptomatic, other than the initial rash!

Re: Why I’m Digging Deep Into Alzheimer’s

#90

Post by ggambetta »

gk1 wrote: post #57
ggambetta wrote: post #29

Earlier quoted context omitted.

I strongly disagree - he should get credit for all the good things he does, regardless of the reasons . Within reason - the end doesn't justify the means.

The person you're responding to was being sarcastic.

I'm aware. I wanted to make my own position very clear.
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