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How Ketogenic Diets Curb Inflammation in the Brain

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Re: How Ketogenic Diets Curb Inflammation in the Brain

#21
post #14
post #3

Earlier quoted context omitted.

Another problem is keto seems difficult to sustain over the long term. People drop off and regain all of their weight.

Modified keto where a higher amount of protein is permitted is much easier to stick to (i.e. 30% protein).. to stay within 0.5-1.5 mmol/L BHB

I thought the only real limit for keto was on non fiber carbs? Is there typically a max ratio on protein too?

Re: How Ketogenic Diets Curb Inflammation in the Brain

#22
post #14
post #3

Earlier quoted context omitted.

Another problem is keto seems difficult to sustain over the long term. People drop off and regain all of their weight.

Modified keto where a higher amount of protein is permitted is much easier to stick to (i.e. 30% protein).. to stay within 0.5-1.5 mmol/L BHB

Not easier to stick to economically though...

Re: How Ketogenic Diets Curb Inflammation in the Brain

#24
post #14

Earlier quoted context omitted.

Modified keto where a higher amount of protein is permitted is much easier to stick to (i.e. 30% protein).. to stay within 0.5-1.5 mmol/L BHB

I thought the only real limit for keto was on non fiber carbs? Is there typically a max ratio on protein too?

Gluconeogenesis can work off excess protein, too. Also, excess protein raises insulin, which is tied directly to weight gain.

Re: How Ketogenic Diets Curb Inflammation in the Brain

#25
post #3
post #2

The problem with basically all of the keto science (this study included) is that it doesn't adequately differentiate between the effects of a ketogenic diet and simple caloric restriction: > In rodents, ketogenic diets – and caloric restriction, in general – are known to reduce inflammation, While there is some science showing differences in calorically balanced diets that vary in macronutrient composition, the truth…

Another problem is keto seems difficult to sustain over the long term. People drop off and regain all of their weight.

Every article states this, but personally the keto diet foods are exactly what I normally crave and want to gorge on: meat, fish, nuts, avocado, butter, double cream, low carb root vegetables, cured meats, cheese, what's not to love? It doesn't take long at all to retrain your palate to understand that rich flavours come from high fat food, not sugars.

Re: How Ketogenic Diets Curb Inflammation in the Brain

#26
post #2

The problem with basically all of the keto science (this study included) is that it doesn't adequately differentiate between the effects of a ketogenic diet and simple caloric restriction: > In rodents, ketogenic diets – and caloric restriction, in general – are known to reduce inflammation, While there is some science showing differences in calorically balanced diets that vary in macronutrient composition, the truth…

> the point is the important difference with keto is that for some people it helps them comply to a calorically balanced diet, not that the macronutrient composition is making a difference.

The whole point of Keto diets is that the macronutrient composition is what makes compliance easy. So, you can’t really extricate macronutrient composition since a diet needs to be followed in order to be effective.

Re: How Ketogenic Diets Curb Inflammation in the Brain

#27
post #2

The problem with basically all of the keto science (this study included) is that it doesn't adequately differentiate between the effects of a ketogenic diet and simple caloric restriction: > In rodents, ketogenic diets – and caloric restriction, in general – are known to reduce inflammation, While there is some science showing differences in calorically balanced diets that vary in macronutrient composition, the truth…

> the point is the important difference with keto is that for some people it helps them comply to a calorically balanced diet, not that the macronutrient composition is making a difference. The whole point of Keto diets is that the macronutrient composition is what makes compliance easy. So, you can’t really extricate macronutrient composition since a diet needs to be followed in order to be effective.

Sure, mind body connection is everything, but there are many keto proponents that argue that controlling for calories, keto still produces superior outcomes. Outside of extreme cases like epilepsy, there is not really any reason to think that's true.

Keto is one of many strategies that people use to comply to consuming the right number of calories.

Re: How Ketogenic Diets Curb Inflammation in the Brain

#28
post #27

Earlier quoted context omitted.

> the point is the important difference with keto is that for some people it helps them comply to a calorically balanced diet, not that the macronutrient composition is making a difference. The whole point of Keto diets is that the macronutrient composition is what makes compliance easy. So, you can’t really extricate macronutrient composition since a diet needs to be followed in order to be effective.

Sure, mind body connection is everything, but there are many keto proponents that argue that controlling for calories, keto still produces superior outcomes. Outside of extreme cases like epilepsy, there is not really any reason to think that's true. Keto is one of many strategies that people use to comply to consuming the right number of calories.

> but there are many keto proponents that argue that controlling for calories, keto still produces superior outcomes

The high fat, low carbs position is that excessive carbs create an endocrine disorder where the body is storing incoming calories in fatty tissue, thus making it unavailable as energy. This causes the body to respond in two ways: 1) eating more food, and 2) expending less energy. The key is that the energy balance equation has two variables, not one. There is the amount of calories that are consumed and then the amount of calories that are expended.

So, it is correct to say that a ketogenic diet, when compared to another diet consisting of the same number of calories, cannot lead to more weight loss as a result of calorie intake. But the ketogenic diet could, in theory, produce comparatively more weight loss by fixing the endocrine system disorder and allowing calories stored in fatty tissue to be used as energy. This would manifest itself as the person on the ketogenic diet being more active and feeling like they have more energy.

I'm not saying that this is, in fact, what is happening, just that it is a plausible theory. In my opinion, the theoretical underpinnings of the low carb, high fat hypothesis seem more plausible to me, but neither side can actually claim that the science supports them, because the studies that need to be done (randomized controlled trials of various types of diets), have simply never been done.

Re: How Ketogenic Diets Curb Inflammation in the Brain

#29
post #3

Earlier quoted context omitted.

Another problem is keto seems difficult to sustain over the long term. People drop off and regain all of their weight.

I've tried tons of diets over the years and keto is by far the only one I've had success with maintaining long term. Even when I take a cheat day, carbs just don't taste that good any more so I end up feeling bloated and go right back on keto.

I've noticed this too, not even with full keto even. When I eat healthier things regularly (veggies and chicken instead of burgers and fries, etc), sweet or carby things taste good but they don't compel me, UNLESS I lapse for a few days. Then the carb cravings come back and I have to work and fight them for days or weeks to reset back to healthy mode.
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