Live data from Hacker News

Too much fructose can damage your liver, just like too much alcohol

sugarscience.ucsf.edu

1–10 of 166 posts

Re: Too much fructose can damage your liver, just like too much alcohol

#2
Without saying how much is too much :)

I wanted to know because it is probably really hard to reach without processing the sugar. IIRC dates are most fructose dense food we can find in nature. How many dates would be enough to damage my liver?

It would probably be hard to hurt your liver with alsohol as well, if you limit yourself to unprocessed alcohol (i.e.: by eating off fruits).

Re: Too much fructose can damage your liver, just like too much alcohol

#4
post #2

Without saying how much is too much :) I wanted to know because it is probably really hard to reach without processing the sugar. IIRC dates are most fructose dense food we can find in nature. How many dates would be enough to damage my liver? It would probably be hard to hurt your liver with alsohol as well, if you limit yourself to unprocessed alcohol (i.e.: by eating off fruits).

I suspect there's no good answer to that question. People vary widely. Some people drink lots of alcohol for years with relatively unscathed livers and others get cirrhosis pretty quickly.

But your instinct is right that fructose that's bound up in real fruit isn't typically the problem. It's unbound fructose like you find in agave nectar or HFCS.

Re: Too much fructose can damage your liver, just like too much alcohol

#5
post #3

Just wanna say that my wife has a PhD in nutrition and this isn't news to us. We've "known" that unbound fructose is hard on the liver for years.

What isn't hard on your liver these days? Most drugs undergo metabolism and activation through the CYP450 system. Meaning that those drugs which clear hepatically are most likely hard on your liver in the long run.

Re: Too much fructose can damage your liver, just like too much alcohol

#8
post #2

Without saying how much is too much :) I wanted to know because it is probably really hard to reach without processing the sugar. IIRC dates are most fructose dense food we can find in nature. How many dates would be enough to damage my liver? It would probably be hard to hurt your liver with alsohol as well, if you limit yourself to unprocessed alcohol (i.e.: by eating off fruits).

I've read Lustig's book, and my recollection is that he says that more than 10% of your daily calories from (all, both added sugar and naturally included sugar, if I remember correctly) sugar is too much. So if you're eating 2000 calories/day, then 200 calories from sugar, which means 200/4 = 50 grams total (including added sugar).

Separately, on the sugar science website they say:

> our scientific team recommends keeping all added sugars below the recommended limits of 6 teaspoons/day (25g) for women and 9 teaspoons (38g) for men.

http://sugarscience.ucsf.edu/sugar-faq.html

Re: Too much fructose can damage your liver, just like too much alcohol

#9
post #4
post #2

Without saying how much is too much :) I wanted to know because it is probably really hard to reach without processing the sugar. IIRC dates are most fructose dense food we can find in nature. How many dates would be enough to damage my liver? It would probably be hard to hurt your liver with alsohol as well, if you limit yourself to unprocessed alcohol (i.e.: by eating off fruits).

I suspect there's no good answer to that question. People vary widely. Some people drink lots of alcohol for years with relatively unscathed livers and others get cirrhosis pretty quickly. But your instinct is right that fructose that's bound up in real fruit isn't typically the problem. It's unbound fructose like you find in agave nectar or HFCS.

Why is real fruit not a problem but HFCS is? Dates sugar content is mostly sucrose which is broken down in the small intestine very rapidly into 50/50 glucose/fructose while HFCS is typically 45/55 glucose/fructose.

Once one sucrose is metabolized by sucrase it hits the bloodstream as glucose and fructose no different than HFSC.

Doesn't only matter in the end how much fructose you consume regardless of whether enters your body bound as sucrose or not as HFCS?

Can you point to some more information are the differences?

Re: Too much fructose can damage your liver, just like too much alcohol

#10
post #8
post #2

Without saying how much is too much :) I wanted to know because it is probably really hard to reach without processing the sugar. IIRC dates are most fructose dense food we can find in nature. How many dates would be enough to damage my liver? It would probably be hard to hurt your liver with alsohol as well, if you limit yourself to unprocessed alcohol (i.e.: by eating off fruits).

I've read Lustig's book, and my recollection is that he says that more than 10% of your daily calories from (all, both added sugar and naturally included sugar, if I remember correctly) sugar is too much. So if you're eating 2000 calories/day, then 200 calories from sugar, which means 200/4 = 50 grams total (including added sugar). Separately, on the sugar science website they say: > our scientific team recommends ke…

So one orange, a large apple and a banana per day will hurt my liver (totaling 63 grams of sugar[1])?

Where is the scientific evidence supporting this?

[1] http://www.sugarstacks.com/fruits.htm

Post reply on HN