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Sugar alters hormones and metabolism, sets stage for obesity and diabetes

aeon.co

101–110 of 221 posts

Re: Sugar alters hormones and metabolism, sets stage for obesity and diabetes

#101

The largest hormonal change we experience isn't puberty - it's night, under the aegis of the master hormone melatonin. Almost every hormone changes. I was overweight and had an appetite out of control a couple decades ago. For other health reasons, I adopted a natural night (real dark, can't see you hand in front of your face) and exactly the same lights on and lights off time. My extra weight vanished. My appetite d…

This sounds very wooey. Do you have anything to show this isn't the result of you wanting to change, changing habits, and your excitement at attempting change carrying through to produce some kind of placebo effect? I get similarly suspicious when people talk about how going on keto radically changed how they felt. Maybe it is true, but in an sea of anecdotes, it's really hard to figure out what is real. Do you notic…

There's no way to demonstrate that as one individual, full stop. The burden of proof you require to consider whether a valuable benefit could potentially be derived is unacquirable.

A more interesting test is to measure the difficulty of trying a certain anecdote yourself. How easily can you 'black out' your bedroom and sit, lay, or sleep in it for a 10 hour window at night for 30 days in a row?

If you can do such a test easily, and you are invested in seeing a certain change that you think may result from it, then it does you no material harm to try it. Worst case scenario, you lose sleep for a few days and abort the experiment. Best case scenario, it has a positive impact. The results could be anywhere between those two endpoints.

So, that makes this a 'safe' test to apply to your own personal body system, which is not necessarily applicable to any others.

Anecdotes that require you to alter what you ingest (food, water, supplements, medicines etc) are much riskier, yet people constantly try these out endlessly under the rubric of "diets" without a second thought for the potential of months of damage to their gut biome, muscle mass, hormone levels, and so on. It's been demonstrated by a vast array of people that it's relatively safe to cut out all the sugar from your diet, but you have to make sure you don't let your blood sugar levels fall too low in the process.

Anecdotes that require you to alter your body (e.g. stomach stapling) are even riskier than those, as we have very little experience in this space compared to diets or other non-consumption non-modification approaches.

You are absolutely correct to be suspicious, but consider also the level of suspicion appropriate for the context. "Try blackout curtains for a month at night and charge your phone face down" is a far lower bar to be 'worth a shot' than "Remove all carbs from your diet". And if you see others failing to take this into account, remind them of the inherent level of risk in what they're considering. It's not always about being right or wrong, but instead about e.g. "how much harm could come to me if I try keto diet?".

EDIT: There's very much a personal overtone to these risk assessments as well. My personal mental stability hinges critically on getting enough sleep, so I am unusually wary of anything that messes with sleep, because I need mental stability far more than I need the benefits such an experiment may or may not produce for me.

EDIT: Harness the placebo effect! Believe that what you're trying could help when you try it. If you're doubtful and pessimistic and cynical about something you're trying, be especially careful to focus every day on why you're trying it. Doing so makes it more likely that the placebo effect will enhance your results, and less likely that the nocebo effect will diminish them. This relates directly to a lot of "woo-woo" thinking, but apply my logic above. What's the level of risk of trying a placebo-welcoming approach? You could mislead yourself into thinking something helped when it didn't. Keeping a careful journal about your experiments is an effective treatment for that problem for many folks, and the placebo effect is really powerful. No point in setting aside a useful tool just because it's mind-body.

Re: Sugar alters hormones and metabolism, sets stage for obesity and diabetes

#102
post #28
post #24

Earlier quoted context omitted.

If butter is the only thing you removed from your diet, you must have been eating an incredible amount of it?!

No, butter makes the other stuff more delicious, making you eat just a little more each time.

I find a great substitute is olive oil where I'd use butter for non-cooking (eg. instead of butter on pasta or instead of butter on bread). It's not quite as tasty but still a huge improvement over dry, and it's healthier.

For cooking, I understand olive oil is unhealthy (I think you create carcinogens as a side-effect), as are many other oils, but that coconut oil doesn't do this because of its different melting temperature.

Re: Sugar alters hormones and metabolism, sets stage for obesity and diabetes

#103
post #57

Earlier quoted context omitted.

Honey has a lower glycemic index/insulin response than sucrose.

but it occupies liver with processing fructose which iirc is disruptive to ketone production and does maintain a level of blood sugar that prevents body from entering ketosis.

If you’re purposefully consuming normal levels of carbohydrates you’re not going to be in ketosis anyways. Unless you’re maintaining a ketogenic diet there’s no reason to worry about your glycosis/ketosis state after a meal. A teaspoon of honey isn’t going to ruin your body. Likewise, if you’re over indulging it doesn’t matter much if it’s “better” sugar or “worse” sugar. I’m willing to bet the poster isn’t drinking a honey sweetened soda.

Re: Sugar alters hormones and metabolism, sets stage for obesity and diabetes

#104

Earlier quoted context omitted.

This sounds very wooey. Do you have anything to show this isn't the result of you wanting to change, changing habits, and your excitement at attempting change carrying through to produce some kind of placebo effect? I get similarly suspicious when people talk about how going on keto radically changed how they felt. Maybe it is true, but in an sea of anecdotes, it's really hard to figure out what is real. Do you notic…

There's no way to demonstrate that as one individual, full stop. The burden of proof you require to consider whether a valuable benefit could potentially be derived is unacquirable. A more interesting test is to measure the difficulty of trying a certain anecdote yourself. How easily can you 'black out' your bedroom and sit, lay, or sleep in it for a 10 hour window at night for 30 days in a row? If you can do such a…

It's not that I think it is risky; there's probably no risk at all from making a room darker when you go to sleep. I know people who can't sleep without a sleeping mask and they've been alternately skinny and fat all the same.

What I'm asking is whether that test, as an individual, can actually prove anything? What you think is an actual effect might not be any effect at all. Without something more rigorous, your "test" is that of a magician. It's easy to forget how suggestible we are as humans.

Do you believe that if you pray to god to confirm himself to you and you feel a "burning in your bosom" that the Book of Mormon and the LDS church are right about reality?

Re: Sugar alters hormones and metabolism, sets stage for obesity and diabetes

#105
post #21

Earlier quoted context omitted.

I hear these anecdotes in many forms, and in my experience the real shared causative factor is making a decision to change, and acting on it. I don't know if it matters what that change is, as long as it's healthy and changes the math of caloriesin - caloriesout. In other words, I wonder if it's the decision and willingness to make hard changes, rather than the specific nature of those changes, which is the real acti…

Here's an anecdote the other direction. One of our employees decided to cut out fast food completely. Total weight loss in over 6 months of doing this? 0 pounds. Why? Because his at-home diet was still full of sugar and carbs (and he admitted as much..."I'll never give up bread!") Meanwhile, I did a low-carb "lazy Keto" diet where all I did was keep carbs under 20g net per day. I continued to eat fast food at least a…

Another anecdote: I'm in the "I'll never give up bread!" camp; I have never been on any kind of specialized diet, and I have never been obese. At one point I wanted to lose 10 LB, and I just counted calories, and it worked, albeit slowly.

Given that bread is a fairly old food, while the obesity problem seems recent, something seems off with the idea that we should all be on a keto diet.

Re: Sugar alters hormones and metabolism, sets stage for obesity and diabetes

#106
post #81

Earlier quoted context omitted.

if you ate 0 grams of sugar for more than a couple of weeks you would die No you absolutely would not. Your body can synthesize glucose from protein and fat, you can survive indefinitely on zero sugar. This is called ketogenic diet.

Considering that many essential nutrients are provided by plants which also provide sugars, you'd have to eat synthetic 'food' in order to avoid all sugars.

> Considering that many essential nutrients are provided by plants

None that I can think of that are proven "essential" in the absence of all carbs. "Phytonutrients" aren't proven essential. Vitamin C ("ascorbic acid") is 100% inessential & optional in the presence of plenty of the (actually essential) ascorbic molecules that are all furnished by fresh meat, including carnitine, creatine etc.

For homo sapiens, there is no essential carbohydrate and no essential plant food. Something to chew on!

Re: Sugar alters hormones and metabolism, sets stage for obesity and diabetes

#107
post #93

Earlier quoted context omitted.

Considering that many essential nutrients are provided by plants which also provide sugars, you'd have to eat synthetic 'food' in order to avoid all sugars.

I guess technically you are right, even meat has some carbs in it because muscles hold some glycogen. The closest thing I can quote is the experiment that Vilhjalmur_Stefansson and Karsten Anderson took part in, eating only meat for a few years https://en.wikipedia.org/wiki/Vilhjalmur_Stefansson#Low-carb... http://inhumanexperiment.blogspot.com.cy/2009/09/two-brave-m... In the end, the one-year project stretched to f…

> I guess technically you are right, even meat has some carbs in it because muscles hold some glycogen

Near-zero because muscle glycogen is used up upon death in a process called "rigor mortis" (not the case for liver glycogen however AFAIK). The fatty marbling luckily remains.

Re: Sugar alters hormones and metabolism, sets stage for obesity and diabetes

#108
post #41

Earlier quoted context omitted.

"Calories count, no matter where they are from." This is the exact point the article is proving wrong.

It doesn't really prove it wrong. If you eat 3000 calories of butter every day, you're gonna get fat. In that sense, a calorie is a calorie.

>In that sense, a calorie is a calorie.

This has been thoroughly disproven for ages -- starting with the naive assumption that you can just eat X amounts of anything and it doesn't affect anything else in your health/apetite/metabolism.

Re: Sugar alters hormones and metabolism, sets stage for obesity and diabetes

#109

The CDC says 34% of US adults have pre-diabetes, and of those, 88% are undiagnosed[1]. Yes, about 29% of US adults have un-diagnosed pre-diabetes, or about 74 million people. I think a significant cause is that testing blood glucose is thought of as something that only diabetics do, and as a result, most people have no idea how their bodies respond to meals they'd consider normal. The feedback loop is completely open…

You can do an a1c test at home or in the doctor to identify chronically elevated glucose (prediabetes). It's insensitive to time of day or fasting status you can just take it every few years or so at your convenience.

Continuous blood sugar monitoring is probably overkill given how easy and cheap a1c tests are now.

Blood pressure, on the other hand, is still a nightmare. A good way of reliably and simply measuring resting blood pressure would be a game-changer.

Re: Sugar alters hormones and metabolism, sets stage for obesity and diabetes

#110

Earlier quoted context omitted.

+1 IIRC both combat divers and people with certain kinds of epilepsy benefit from carb free diets as it reduces risk of passing out (for combat divers with rebreathers) and epileptic attacks (for epileptics).

What do you think a 'carb free' diet excludes? What does it include? I'm asking, because I'm genuinely confused by the fact that all plant (veggies, fruits, seeds/grains, all of it) matter contains sugars. Do a lot of folks really sustain themselves on meat alone? Hell, not even my 100lb german shepherd can live on only meat (IIRC carnivores frequently eat stomach contents of herbivores they kill/find to get nutrient…

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