Live data from Hacker News

I was in the MAPS MDMA for PTSD study

psymposia.com

41–50 of 159 posts

Re: I was in the MAPS MDMA for PTSD study

#41
post #8

Earlier quoted context omitted.

> For decades, there has been a near complete effective block on medical research for certain classes of drugs. In the US. One wonders why such a study wasn't carried out in a less puritan country.

It's because the real reason that testing these drugs is illegal isn't USA puritan values/laws. It's because they aren't patented. The synthetic opioids that drug companies are dumping on the population these days are many times more dangerous, but they make a profit for big companies, so they are legal. Powerful drug companies influence research worldwide. They want no competition from drugs that would be generic fr…

This is a big issue. Clinical studies to get a chemical approved for therapeutical use are very expensive, and since most of the chemicals were first explored a long time ago, they can't be patented anymore, so no pharmaceutical company would fund the studies since they won't be able to be the sole provider of that drug (at a premium cost), and public funding for clinical studies is quite low.

Re: I was in the MAPS MDMA for PTSD study

#42
post #30

I feel like there has to be a good amount of people in the world who take psychedelics on a regular basis. At least more so than your average person. I'd imagine they are still broken, shattered, and lost individuals. Maybe some people have accessed some secret knowledge on their trips. But for the vast majority, I doubt that's the case. I am not saying that there is no benefit, especially for an extreme case like th…

I've experienced a trauma-induced anxiety disorder and mdma experiences. You seem to reach a certain level of insight but then suddenly turn strangely dismissive.

> the high you get is a distraction from the pain you are feeling

Sort of. The feeling is of an assurance, a joyful security that releases you to be able to confront the pain without (as much) fear. There's also a shift in perspective that let's you know that a different way of feeling is possible. That's surprisingly powerful.

> are you just finally looking at what you didn't want to all these years?

Yes, exactly this.

> Do you need to take psychedelics to look?

Perhaps not, but anecdotal evidence and a growing amount of research suggests it helps tremendously, especially in cases where it is very hard for people to look at themselves whilst sober.

> I wouldn't be surprised if we find out that psychedelics was just a fad.

I don't see how this follows from anything you've said.

Re: I was in the MAPS MDMA for PTSD study

#43
post #39

Earlier quoted context omitted.

What is an MDMA session?

When a patient sits with a therapist under the influence of MDMA, which typically consists of two doses (100-120mg initially, then 70mg a few hours later) spread over an 6-8 hour period. The patient is largely experiencing their own internal process, but at times the therapist is there to help guide and comfort. Before and after the session there is conventional psychotherapeutic follow-up.

Are you sure about the doses? Doesn't sound overly therapeutic to me tbh

Re: I was in the MAPS MDMA for PTSD study

#44

Earlier quoted context omitted.

What is an MDMA session?

A guided therapy session with a licensed practitioner which involves the patient taking a small dose of MDMA

Not typically a particularly small dose. Sometimes a fairly large dose, in the 150mg range.

Re: I was in the MAPS MDMA for PTSD study

#45
post #39

Earlier quoted context omitted.

What is an MDMA session?

When a patient sits with a therapist under the influence of MDMA, which typically consists of two doses (100-120mg initially, then 70mg a few hours later) spread over an 6-8 hour period. The patient is largely experiencing their own internal process, but at times the therapist is there to help guide and comfort. Before and after the session there is conventional psychotherapeutic follow-up.

Is it possible to do this, today, anywhere in the world (without getting into a study, which seems hard, especially in another country)? I am looking for help for somebody close to me.

Re: I was in the MAPS MDMA for PTSD study

#46
post #21

Every time articles like this appear on Hacker News it fills me with joy. I have personally watched a much older person heal extensive personal trauma with just one MDMA session, and to this day I regard it as a miracle that seemed impossible prior to the treatment. MAPS is just entering into their Stage III research process after being granted a "breakthrough therapy" by the FDA ( https://www.cbsnews.com/news/fda-de…

What is an MDMA session?

Amazing book to answer that question:

https://www.amazon.com/Secret-Chief-Revealed-Myron-Stolaroff...

Re: I was in the MAPS MDMA for PTSD study

#47
post #43
post #39

Earlier quoted context omitted.

When a patient sits with a therapist under the influence of MDMA, which typically consists of two doses (100-120mg initially, then 70mg a few hours later) spread over an 6-8 hour period. The patient is largely experiencing their own internal process, but at times the therapist is there to help guide and comfort. Before and after the session there is conventional psychotherapeutic follow-up.

Are you sure about the doses? Doesn't sound overly therapeutic to me tbh

Based on what? They're going for a different result than just getting high - the doses aren't likely to match what one might take in a club.

Re: I was in the MAPS MDMA for PTSD study

#48
post #21

Every time articles like this appear on Hacker News it fills me with joy. I have personally watched a much older person heal extensive personal trauma with just one MDMA session, and to this day I regard it as a miracle that seemed impossible prior to the treatment. MAPS is just entering into their Stage III research process after being granted a "breakthrough therapy" by the FDA ( https://www.cbsnews.com/news/fda-de…

What is an MDMA session?

A short web page I put together with some more info: https://rollsafe.org/mdma-therapy/

Re: I was in the MAPS MDMA for PTSD study

#49
post #30

I feel like there has to be a good amount of people in the world who take psychedelics on a regular basis. At least more so than your average person. I'd imagine they are still broken, shattered, and lost individuals. Maybe some people have accessed some secret knowledge on their trips. But for the vast majority, I doubt that's the case. I am not saying that there is no benefit, especially for an extreme case like th…

Wow, you don't have any experience with these drugs, do you?

Re: I was in the MAPS MDMA for PTSD study

#50
post #39

Earlier quoted context omitted.

What is an MDMA session?

When a patient sits with a therapist under the influence of MDMA, which typically consists of two doses (100-120mg initially, then 70mg a few hours later) spread over an 6-8 hour period. The patient is largely experiencing their own internal process, but at times the therapist is there to help guide and comfort. Before and after the session there is conventional psychotherapeutic follow-up.

The dosages used in the FDA Phase 3 research are 80mg or 120mg initial dose followed by either 40mg or 60mg 1.5-2 hrs later, respectively.
Post reply on HN