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Launch HN: Forever Labs (YC S17) – Stem-Cell Banking

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Launch HN: Forever Labs (YC S17) – Stem-Cell Banking

#1
Hey HN! I’m Mark, one of the founders of Forever Labs (https://foreverlabs.com). We bank your stem cells to help you live healthier longer.

I’ve spent the last 15 years developing therapies using bone mesenchymal stem cells for treatment of neurological injury and disease. Over these years, preclinical research of mine and others has translated to over 500 clinical trials currently employing these cells for treatment of stroke, heart disease, dementia, and more.

This is especially good news when it comes to diseases such as ischemic stroke, where we haven’t had a new approved therapeutic in over 20 years. It is no exaggeration to say that stem cell therapy is creating opportunities for treatment where few existed.

However, there is a problem. To put it simply: 1) Your own stem cells treat you best, 2) your stem cells decline with age, and 3) you need your stem cells most for diseases that affect you when you are old.

Our solution is to cryopreserve your stem cells now, creating a reservoir of youthful stem cells that you draw upon throughout your life.

In addition, we are developing applications for these cells that not only treat age-related disease, but actually delay their onset.

Of course, few matters in biology and medicine can be “simply put”, and we’d be happy to discuss details below!

Re: Launch HN: Forever Labs (YC S17) – Stem-Cell Banking

#8
post #3

How old is too old to use my stem cells/ I'm 64 in 2 weeks.

The decline in functionality begins to be detectable between 20-40, and accelerates with age. This study has a number of measures regarding bone mesenchymal stem cells (which are included in what we collect and store):

https://www.ncbi.nlm.nih.gov/pubmed/18248663

Ideally, we all store at 18. However, my mother just stored at 70. Her mother lived to 93, and two of her aunts over 100. She decided that in 10 years, she might be glad she did. My own cells are 40. I am 42.

Re: Launch HN: Forever Labs (YC S17) – Stem-Cell Banking

#9
post #5

What happens to my stem cells if you go out of business?

We currently have enough clients that the annual storage fees paid in more than cover the costs of our repository. We are actively pursuing two options to address this possibility: 1) The cell banking service is a separate entity, and all of us who have banked continue to pay into that entity keeping it funded, even if Forever Labs were to dissolve, and 2) An insurance policy covers long-term storage if Forever Labs dissolves.

All of our cells are banked, as are my wife's and family members. We are addressing this.

That said, your cells remain your own. At any time, we will ship them to another biorepository for $300.

Re: Launch HN: Forever Labs (YC S17) – Stem-Cell Banking

#10

This is a neat startup idea. Can you point me to research that this works? I saw some blog posts but I couldn't find any research articles.

Thanks! Here's a small collection of research:

https://foreverlabs.com/blogs/research

Also, here are some recent clinical trials using autologous bone marrow for treatment of heart disease or stroke:

https://clinicaltrials.gov/ct2/show/NCT01716481 https://clinicaltrials.gov/ct2/show/NCT02438306 https://clinicaltrials.gov/ct2/show/NCT01569178 https://clinicaltrials.gov/ct2/show/NCT01652209

Also, searching https://clinicaltrials.gov for 'autologous mesenchymal' will produce many results to peruse.

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