The problem is this will never get funded or passed due to the Big Pharma lobbyists.
That might have been true 5-10 years ago, but there's a lot of $$$ in the industry now...enough to fund development of something like this.
Marijuana Compound Removes Toxic Alzheimer’s Protein from the Brain
31–40 of 54 posts
Re: Marijuana Compound Removes Toxic Alzheimer’s Protein from the Brain
#32Hmm, seems like it's time to seriously consider extracting some THC and CBD. I'm looking at this: https://magicalbutter.com/ . Anyone have some experience with this type of gear?
> Hmm, seems like it's time to seriously consider extracting some THC and CBD
It's great if researchers can find new treatments, but I think people get over-enthusiastic with medical cannabis
> Anyone have some experience with this type of gear?
I would rather vaporize weed. Very simple and (likely) safe, effect is immediate and it's easier to adjust the quantity as you go.
I'm not sure about the gear but I cooked cannabis butter a few times (quite easy without special equipment). It's more difficult to control the quantity. You need to be careful to not ingest too much cannabis, because then it's too late and it can be very powerful. Conversely, if not enough, you have to wait for an hour or so to be sure. Another issue I had is that I ended up with a nice cake that I had to ration carefully as it was very psychoactive. I couldn't simply eat it whenever I felt like. Besides, the weed doesn't add a good taste (at best neutral, depending on the quantity).
I'm sure that these issues can be overcome with some experience but is it worth the trouble?
Re: Marijuana Compound Removes Toxic Alzheimer’s Protein from the Brain
#33Problems with this terrible title: 1. In vitro petri dish testing is a million light years away from showing a compound works in humans. 2. This is a particularly bad problem in brain diseases as getting your compound to cross the blood-brain barrier in correct therapeutic quantities is extremely difficult. 3. We have lots of direct antibodies that kill beta amyloid in vivo that are very advanced in human trials. The…
> start hitting the downvote button
I know this will get downvoted but it's too bad there's no downvote button on HN
Re: Marijuana Compound Removes Toxic Alzheimer’s Protein from the Brain
#34Problems with this terrible title: 1. In vitro petri dish testing is a million light years away from showing a compound works in humans. 2. This is a particularly bad problem in brain diseases as getting your compound to cross the blood-brain barrier in correct therapeutic quantities is extremely difficult. 3. We have lots of direct antibodies that kill beta amyloid in vivo that are very advanced in human trials. The…
> start hitting the downvote button I know this will get downvoted but it's too bad there's no downvote button on HN
downvoted for irony
Re: Marijuana Compound Removes Toxic Alzheimer’s Protein from the Brain
#35Hmm, seems like it's time to seriously consider extracting some THC and CBD. I'm looking at this: https://magicalbutter.com/ . Anyone have some experience with this type of gear?
> Hmm, seems like it's time to seriously consider extracting some THC and CBD It's great if researchers can find new treatments, but I think people get over-enthusiastic with medical cannabis > Anyone have some experience with this type of gear? I would rather vaporize weed. Very simple and (likely) safe, effect is immediate and it's easier to adjust the quantity as you go. I'm not sure about the gear but I cooked ca…
Thanks for the suggestions. Your psychoactive cake sounds very intriguing!
Re: Marijuana Compound Removes Toxic Alzheimer’s Protein from the Brain
#36Earlier quoted context omitted.
Thank you. I think I will give it a try as well. We are running out of options for my father - perhaps this would be a good Hail Mary.
Just do your research on dosing and what your father will tolerate. It may be more beneficial to get one of the strands that gives no high. Good luck , I'm sure it's not easy.
Thank you. Yes, it is figuring out the dosing that concerns me.
Re: Marijuana Compound Removes Toxic Alzheimer’s Protein from the Brain
#37Hmm, seems like it's time to seriously consider extracting some THC and CBD. I'm looking at this: https://magicalbutter.com/ . Anyone have some experience with this type of gear?
I read a number of reviews of it while considering getting one. It seems to me the most error-prone part of extracting is the decarboxylation, and this device doesn't do that. (There apparently is a device that does that, but the name escapes me just now.) So it doesn't seem to provide a whole lot of value.
Re: Marijuana Compound Removes Toxic Alzheimer’s Protein from the Brain
#38Hmm, seems like it's time to seriously consider extracting some THC and CBD. I'm looking at this: https://magicalbutter.com/ . Anyone have some experience with this type of gear?
I've had good results with a normal crock pot on the high setting overnight.
That sounds like worth trying, given your experience.
Re: Marijuana Compound Removes Toxic Alzheimer’s Protein from the Brain
#39Problems with this terrible title: 1. In vitro petri dish testing is a million light years away from showing a compound works in humans. 2. This is a particularly bad problem in brain diseases as getting your compound to cross the blood-brain barrier in correct therapeutic quantities is extremely difficult. 3. We have lots of direct antibodies that kill beta amyloid in vivo that are very advanced in human trials. The…
It's still fun to read about, although acknowledged I have the privilege of not being directly affected by Alzheimer's.
It's also really useful when there's comment on Hacker News pointing out the things that have been glossed over in an over-hyped article, so thanks. (no sarcasm intended)
Re: Marijuana Compound Removes Toxic Alzheimer’s Protein from the Brain
#40Problems with this terrible title: 1. In vitro petri dish testing is a million light years away from showing a compound works in humans. 2. This is a particularly bad problem in brain diseases as getting your compound to cross the blood-brain barrier in correct therapeutic quantities is extremely difficult. 3. We have lots of direct antibodies that kill beta amyloid in vivo that are very advanced in human trials. The…
> start hitting the downvote button I know this will get downvoted but it's too bad there's no downvote button on HN
That's only true if you have less than 500 karma.
Edit: although stories can't be downvoted.