I have no doubt they can. There's so much negative cultural conditioning towards mathematics by eliciting negative emotions that it's ridiculous (i.e. math is scary, math is hard, math is for smart people, etc.). I believe kids who excel at math is not due to them being smarter but due to the bypassing of the cultural conditioning. The bypassing can be due to the parents, teachers, some mentor, or their particular fa…
What makes the difference is that video games aren't compulsory. So they represent true play. Which is what makes them educational, unlike a school curriculum, however much it is tweaked. Well, until something more fun than video games arrives on the scene...