I think it's interesting how the Edith stated Damore had said women were worse at their job, while one of the other women explicitly said he didn't, and the other only mentioned interest in programming. This is similar to the divide I've seen in the media. I have not read the memo in it's entirety, but since the impression I got from reading a few news stories was that Damore had only made his controversial statement…
I think she refers that gender is not binary as you can be straight male, straight female, gay male, gay female, bisexual, asexual, etc.
I am not completely sure but I think there can be mutations where you have 2 chromosomes X and 1 Y. So XXY [1]