Ok, let's assume we find a warm, watery planet like Earth's within ~20 light years, and we figure out a way to travel >= 50% the speed of light, making it somewhat reasonable to get there. If the planet's gravity is greater than 10% different from Earth's, or its Day/Night cycle is much different from Earth's, wouldn't it still be a nightmare to live on. Anatomically modern humans have lived on Earth for 200,000 year…
Even at 50% the speed of light, adding in a fudge factor for acceleration/deceleration, you're still talking about a trip time of 50 yrs. Even if you go all Neon Genesis and send 15 year olds on the journey, they'll be at retirement age by the time they arrive. In other words, you'd almost definitely have to send a generation ship. Which means you'd have to have already figured things like artificial gravity, giving…
[1] disclaimer: I didn't do the math, i just googled the tables.