First Human Embryos Edited in U.S
technologyreview.com
First Human Embryos Edited in U.S
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Re: First Human Embryos Edited in U.S
#2Related: 'Unexpected mutations after CRISPR–Cas9 editing in vivo' http://www.nature.com/nmeth/journal/v14/n6/full/nmeth.4293.h...
Re: First Human Embryos Edited in U.S
#3Related: 'Unexpected mutations after CRISPR–Cas9 editing in vivo' http://www.nature.com/nmeth/journal/v14/n6/full/nmeth.4293.h...
Addressed by the article
Re: First Human Embryos Edited in U.S
#4Related: 'Unexpected mutations after CRISPR–Cas9 editing in vivo' http://www.nature.com/nmeth/journal/v14/n6/full/nmeth.4293.h...
Addressed by the article
Kind of addressed in the article. I'd still like to see more data before calling the issue "addressed".
(Then again, this is a lay-press article, so I don't entirely expect a lot of detail)
Re: First Human Embryos Edited in U.S
#5"Now Mitalipov is believed to have broken new ground both in the number of embryos experimented upon and by demonstrating that it is possible to safely and efficiently correct defective genes that cause inherited diseases."
Seems a little early for such a claim based on embryos that only developed for a few days.
Re: First Human Embryos Edited in U.S
#6The talk is of 'genetic enhancement' but the potential benefit seems more boring and necessary to me: removal of many new and as-yet-unidentified mutations. It is thought that these have been accumulating generation by generation since about 1800 when child mortality started to fall.
Re: First Human Embryos Edited in U.S
#7Earlier quoted context omitted.
Addressed by the article
Kind of addressed in the article. I'd still like to see more data before calling the issue "addressed". (Then again, this is a lay-press article, so I don't entirely expect a lot of detail)
Not sure I would call MIT technology review lay press
Re: First Human Embryos Edited in U.S
#8Related: 'Unexpected mutations after CRISPR–Cas9 editing in vivo' http://www.nature.com/nmeth/journal/v14/n6/full/nmeth.4293.h...
This paper was incredibly sloppy and has been widely dismissed by scientists in the field.
Re: First Human Embryos Edited in U.S
#9"Now Mitalipov is believed to have broken new ground both in the number of embryos experimented upon and by demonstrating that it is possible to safely and efficiently correct defective genes that cause inherited diseases." Seems a little early for such a claim based on embryos that only developed for a few days.
In the US human embryos used for research are restricted from developing for more than two weeks