ITA has a big problem: their follow on to the QPX product that everyone has been talking about is a airline reservation, management etc. system called RES. This is desperately needed since pretty much everyone is running these systems on expensive mainframes with ugly old code bases.
Dan Wienreb did a very interesting talk, "Lisp for High-Performance Transaction Processing" that covered it and a bit on the future of Lisp (for a outline and link to the talk see: http://xach.livejournal.com/225634.html).
RES is a three tier system with Oracle RAC as the backend (pretty much the only choice), stateless Common Lisp middleware and Java with the usual web libraries for the front end. 300 milisecond? general max transaction time, which they weren't finding to be a big issue even with GC.
The problem: someone has to go first. While it's arbitrarily sized/scoped to accommodate American Airlines, Air Canada was going to be the lead customer. In August 2009 they suspended their participation in the project, I strongly suspect due to the general recession/depression in the industry. Switching would be very expensive in all sorts of ways and raw survival almost certainly is taking priority. (ITA has continued developing the system.)
This part/project of ITA is very likely to be a victim of bad timing; I sure can't see Google credibly continuing it, it's all wrong for their service culture, although perhaps it'll get spun off.