An interesting related anecdote on this is that at least in Chrome, adblockers can also interfere with extensions' attempts to load scripts, load stylesheets, or open windows. I maintain an extension with a smallish active userbase (~20k people) and a couple different times I've encountered mysterious failures that were the result of clumsy keyword blocklists in ublock/adblock/etc - for example an extension asset (pa…
If your extension injects resources in the DOM, than a content blocker can interfere with the proper loading or rendering of these resources.
However I am very surprised about your statement that a content blocker extension intefered with your extension assets, my understanding is that should not be possible. You mind disclosing what is your extension?