I used to mine Bitcoin back in 2011 and I lost my wallet.dat file (through several stupid moves on my part). It's got approx 103 BTC in it, anyone is welcome to it, I've given up trying. https://blockchain.info/address/166BuLPWHUjqoqiYp5rGE3B5r5Am...
It had 1,000 BTC in it! He had received them from a generous Bitcoin contributor in the early days who said "here you go, hold on to it, it will be worth something someday."
I still give him a hard time about his $3 million USD mistake...