Bizarre. I've only tried to use Etsy once, figuring it'd be a great place to get some sort of unique jewellery as a gift. It's filled with junk, both of the super-manufactured kind and of the "modern art" kind (someone glues 2 pieces of crap together and wants $500.) I haven't gone back, though I did enjoy the Regretsy blog while it was up. >Etsy’s insistence on running its own servers rather than using cloud-based s…
The cloud is very, very expensive. If you want low cost, you do your own servers for anything under 20 nodes. Which, given the power of modern machines and with unmethered bandwidth, will take you to the millions of user easily. I have setup a streaming website with 500k/d visitors, and it runs on 7 servers for 2000$ a month give or take. That's very, very cheap compared to GAE or AWS.
At stage one, with Stage two is a sweet spot where running your own 5-25 machines makes sense for stable, medium-sized, medium traffic businesses.
After that, though, stage 3 is when gets to be too much for one combination programmer/devops employee to manage in their spare time, and it makes sense to go back to the cloud and have someone else manage all of that for you. A lot of startups focused on rapid growth like to skip step 2 and go straight to this stage. When you outgrow the "do whatever's cheapest" stage of hosting, it can become untenable to explain to your investors that a few thousand in server hardware will probably be adequate for the next few years, and they'll see a nice return of a fraction of an employee per month on hosting if it's done most efficiently.
Somewhere in the stratosphere, stage 4 is when it again becomes more reasonable to hire an internal team to assemble and maintain your computing resources. Perhaps you can instead convince your investors that this is your target? After all, Facebook, Amazon, Google, and Microsoft are on their own hardware...