(Only use the real ASUS power adapters; the no-name 3rd party units overheat, don't provide enough power, or in at least one case, catch fire.)
When I get one in, I put in the Xubuntu USB stick and run the memory diagnostic for an hour. If that passes, I wipe the machine completely and install Xubuntu 16.04LTS. Works fine. All the peripherals are supported. (There was some trouble with 14.04 LTS; the infamous "disappearing cursor" bug affected these units, because they had a certain model of Intel graphics processor. But that's fixed.)
I use one with a $30 USB microscope to help with surface mount soldering. Others run antique Teletype machines. One is used as a normal laptop.