For instance, if you have a graphics tool that briefly flashes screen updates, the problems are much easier to see. On a fast system, you might not only miss an unnecessary refresh of “everything”, you may miss a repeated refresh of the same content.
Also, on slower systems, the cost to generate a frame may delay an entire sequence. Consider something like “live resizing”: on your spiffy machine it seems fluid, on a lesser machine it might be stuttering like crazy. Sometimes you have to cheapen the computations occurring during rendering to make sure it’s OK.