Running MONITOR in production can severely affect performance, by 50% per monitoring client according to the documentation. twemproxy independently exposes some statistics, it's probably safer to do it that way.
# Commandstats
cmdstat_info:calls=1,usec=57,usec_per_call=57.00
cmdstat_cluster:calls=8,usec=211,usec_per_call=26.38
cmdstat_zrange:calls=4,usec=1990,usec_per_call=497.50