As for what I think in general about it: I'm not concerned, worried, or even scared about the effects. If anything, inelegance of brute-force aside, I think there's something very beautiful and awe-inspiring in this discovery, like solving a puzzle or maths conjecture that has remained unsolved for many years.
I remember when I first heard about MD5 and hash functions in general, and thinking "it's completely deterministic. The operations don't look like they would be irreversible. There's just so many of them. It's only a matter of time before someone figures it out." Then, years later, it happened. It's an interesting feeling, especially since I used to crack softwares' registration key schemes which often resembled hash functions, and "reversing" the algorithms (basically a preimage attack) was simply a matter of time and careful thought.
There's still no practical preimage for MD5, but given enough time and interest... although I will vaguely guess that finding SHA-256 collisions probably has a higher priority to those interested.