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Nicotine Normalizes Brain Activity Deficits That Are Key to Schizophrenia

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Re: Nicotine Normalizes Brain Activity Deficits That Are Key to Schizophrenia

#71

Post by maw »

_m8fo wrote: post #62
qrybam wrote: post #38

Tangential self experimentation anecdote: I was intrigued by reports that nicotine can improve cognition in otherwise healthy people so I read through as many studies/articles I could find online. After deciding that I'd done enough research I took the plunge and began self experimenting with 2mg gum. I took it daily throughout the day at regular-ish intervals for around 2-3 months. The affects I experienced were as…

Why not just get more, higher quality sleep? It provides all of the upsides that you mention with no downsides.

You make it sound as though sleep quality were something everyone has control over, which is not at all the case.

Re: Nicotine Normalizes Brain Activity Deficits That Are Key to Schizophrenia

#72

Post by iak8god »

DanBC wrote: post #56
iak8god wrote: post #41

Earlier quoted context omitted.

It looks like about 1/3 of smoking-related deaths are due more to the nicotine than the smoke: https://www.cdc.gov/tobacco/data_statistics/fact_sheets/heal... That's much higher than I'd assumed, and bad news for those who want to claim that e-cigarettes are essentially safe. EDIT: DanBC points out below[1] that it's wrong to assume the cardiovascular disease is caused primarily by nicotine, which is how I came to th…

Which part of your link, or the large surgeon general's report, say that "about 1/3 of smoking related deaths are due more to the nicotine than the smoke"?

Out of 480,317 deaths attributed to cigarette smoking, 160K were due to cardiovascular diseases and metabolic diseases. 160/480 = .3333

This calculation makes the charitable assumption that none of the deaths categorized as Cancer were due to the nicotine itself. The categories are Cancer, Cardiovascular Diseases and Metabolic Diseases, Respiratory Diseases, Perinatal Conditions, Residential Fires, Secondhand Smoke.

Re: Nicotine Normalizes Brain Activity Deficits That Are Key to Schizophrenia

#73

Post by slaveofallah93 »

anigbrowl wrote: post #48

“This defines a completely novel strategy for medication development,” says lead author As someone with schizoaffective problems and raging ADHD, I find quotes like this acutely annoying. I've told every psychiatrist I'eve ever dealt with about the experiential costs/benefits of smoking (and consuming various other recreational drugs). They all nod sagely and say things like 'but smoking is bad' (no shit Sherlock!) w…

Smoking is not the only way you can get nicotine. Have you considered trying nicotine chewing gum or similar?

I find nicotine gum helpful personally.

Re: Nicotine Normalizes Brain Activity Deficits That Are Key to Schizophrenia

#75

Post by return0 »

anigbrowl wrote: post #48

“This defines a completely novel strategy for medication development,” says lead author As someone with schizoaffective problems and raging ADHD, I find quotes like this acutely annoying. I've told every psychiatrist I'eve ever dealt with about the experiential costs/benefits of smoking (and consuming various other recreational drugs). They all nod sagely and say things like 'but smoking is bad' (no shit Sherlock!) w…

Are there not alternatives to smoking for taking nicotine?

Re: Nicotine Normalizes Brain Activity Deficits That Are Key to Schizophrenia

#76

Post by hbosch »

qrybam wrote: post #38

Tangential self experimentation anecdote: I was intrigued by reports that nicotine can improve cognition in otherwise healthy people so I read through as many studies/articles I could find online. After deciding that I'd done enough research I took the plunge and began self experimenting with 2mg gum. I took it daily throughout the day at regular-ish intervals for around 2-3 months. The affects I experienced were as…

For anyone interested in continued reading, I highly suggest the prolific Gwern[0] and his compendium on nootropic dosing[1], and specifically nicotine[2] as it related to the post above.

-

[Scoping urls for ease]

0. https://www.gwern.net/

1. https://www.gwern.net/Nootropics

2. https://www.gwern.net/Nootropics#nicotine-gum

Re: Nicotine Normalizes Brain Activity Deficits That Are Key to Schizophrenia

#77

Post by carlisle_ »

anigbrowl wrote: post #48

“This defines a completely novel strategy for medication development,” says lead author As someone with schizoaffective problems and raging ADHD, I find quotes like this acutely annoying. I've told every psychiatrist I'eve ever dealt with about the experiential costs/benefits of smoking (and consuming various other recreational drugs). They all nod sagely and say things like 'but smoking is bad' (no shit Sherlock!) w…

>Of all the medical professionals I've ever dealt with, psychiatrists are the laziest and least imaginative.

This matches my experiences pretty exactly. It's even worse knowing that psychiatry is not as scientific in some contexts as I've been lead to believe.

Re: Nicotine Normalizes Brain Activity Deficits That Are Key to Schizophrenia

#78

Post by anigbrowl »

tsomctl wrote: post #60
losteric wrote: post #33

Earlier quoted context omitted.

Or just MJ for everything

If you can recommend a strain that helps with ADHD while still allowing you to be alert and cognizant, I would really like to know. I've been looking for years.

I have had some success with 'blueberry' indica strains (named for their fragrant characteristics I believe). I can be incredibly productive with this in the right environment (quiet, minimal interruptions, physically comfortable). But it's harder to shift focus and social interaction (even with intimates) is more of a chore. I don't know that it helps with adhd so much as alleviating anxiety enough to let me focus on what I want to think about.

Re: Nicotine Normalizes Brain Activity Deficits That Are Key to Schizophrenia

#79

Post by samx18 »

anigbrowl wrote: post #48

“This defines a completely novel strategy for medication development,” says lead author As someone with schizoaffective problems and raging ADHD, I find quotes like this acutely annoying. I've told every psychiatrist I'eve ever dealt with about the experiential costs/benefits of smoking (and consuming various other recreational drugs). They all nod sagely and say things like 'but smoking is bad' (no shit Sherlock!) w…

IMO Vaping is a far safer alternative to smoking for getting nicotine.

Re: Nicotine Normalizes Brain Activity Deficits That Are Key to Schizophrenia

#80

Post by spamlord »

anigbrowl wrote: post #48

“This defines a completely novel strategy for medication development,” says lead author As someone with schizoaffective problems and raging ADHD, I find quotes like this acutely annoying. I've told every psychiatrist I'eve ever dealt with about the experiential costs/benefits of smoking (and consuming various other recreational drugs). They all nod sagely and say things like 'but smoking is bad' (no shit Sherlock!) w…

Unfortunately many Chantix users suffer from intense side-effects, and many have committed suicide.
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