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Paper Centrifuge

gizmodo.com

41–50 of 133 posts

Re: Paper Centrifuge

#41
As usual, what you really want to do is read the paper: http://www.nature.com/articles/s41551-016-0009

This is a well-written and very clear paper. It covers several aspects that went unmentioned in the Gizmodo article, and highlights that although building such a device may be trivial, evaluating and studying it is not.

Some highlights: the paper covers how the device was built in detail, including information on the three safety mechanisms used to ensure the operator doesn't get exposed to infected blood (shatterproof plastic capillaries, epoxied sample holders made from drinking straws, and sealing of the capillaries inside two paper discs). It is exclusively made from low-cost materials, but it's more than just a piece of paper, handles and some string (fishing wire).

The paper also covers the physical dynamics of the "paperfuge" in great detail, analyzing its rotational dynamics and building a theoretical model of motion that agrees well with the physical observations (captured with a 6000fps high-speed camera). It also shows that the max RPM varies with disc size, with 125000 RPM for a small disc (5mm diameter). The paper even mentions that this was submitted as a Guiness World Record.

Finally it shows that the paperfuge produces sample separation results on par with electromechanical centrifuges using similar spinning time (1.5min for paperfuge, 2min for centrifuge for plasma separation), and does an analysis of the resulting blood samples.

Re: Paper Centrifuge

#42
Walk into any modern hospital central lab today, look at the life saving technology thats available to us and ask yourself why we still have not figured out how to give other people access to this?

paper centrifuge? come on...

Re: Paper Centrifuge

#43
post #35
post #30

Earlier quoted context omitted.

I'm not really sure what you are trying to say here. If you have a better solution to centrifuge availability than a 20c one made out of paper, please enlighten us.

yes i have a better solution - kill one of those multibillion military projects and redirect the money to buy lifesaving medical equipment to the places that need it. equip research facilities with equipment and provide local training. paper centrifuge? its like a slap on the face.

Those expensive medical machines require a lot of infrastructure to operate properly. You could get a machine there, but you likely couldn't provide it clean and reliable power without additional equipment and technicians to maintain it. Bootstrapping infrastructure is stupendously hard and expensive (and is a huge measure of a country's wealth - a lot of the US wealth is tied up in structural infrastructure like power lines, roads, plants, etc). It's a generational process taking decades to bootstrap.

All the while that is getting built people need help now, and this clever adaptation of a toy fills that niche. Eventually they'll have access to the more advanced modern wonders, but for now this can help people almost immediately.

Re: Paper Centrifuge

#45
post #15
post #6

Earlier quoted context omitted.

It's not: https://diybio.org/2012/06/11/dremelfuge-classic/ But presumably this could be for regions in which even those materials are difficult to obtain.

I use the dremelfuge. It's not particularly safe, but it does get the job done for very basic spin-downs. You don't have really precise RPM control, as well as many other things.

I wonder if you could use a laser tachometer to help dial in the RPM? e.g.

https://www.amazon.com/Digital-Photo-Laser-Tachometer-Contac...

Re: Paper Centrifuge

#46

As usual, what you really want to do is read the paper: http://www.nature.com/articles/s41551-016-0009 This is a well-written and very clear paper. It covers several aspects that went unmentioned in the Gizmodo article, and highlights that although building such a device may be trivial, evaluating and studying it is not. Some highlights: the paper covers how the device was built in detail, including information on th…

Thanks a lot for the summary. It's so hard to look at simple things and see how difficult it is to make them a product, and even harder to see the edge cases that prevent it from being used in healthcare.

I really like that there's a comparison to commercial centrifuges, since that shows the quality of medical care isn't going down simply to be cheap. Overall it looks like a well thought out design.

Re: Paper Centrifuge

#47
post #3

15 mins of human labor per test doesn't sound cheap but I guess you can get the patient to do it themselves. A bit curious, why is a cheap centrifuge hard to build? It seems like a pretty simple device and motors are pretty cheap.

[deleted]

Re: Paper Centrifuge

#48
post #40
post #39

Earlier quoted context omitted.

> kill one of those multibillion military projects and redirect the money And how are the inventors supposed to do that?

we, the citizens who vote are supposed to do that.

So you're criticizing the situation that makes this invention such an improvement, not the invention itself? I certainly understand that, but your comments on first reading to me (and probably to other readers) appear to be criticizing the invention itself, which I and other readers vehemently disagree with.

Re: Paper Centrifuge

#49
post #25

its a nice toy, for kids to learn science. but really, what are we - stuck in the stone age? Its year 2017, there is no reason why those people should not have access to the advanced technology we enjoy today in the west. make a pathetic paper centrifuge and give ourselves a pat on the back, really? What have we become?

Don't underestimate the power of a simple(r) solution. A cheap and reliable solution, readily accesible, is powerful when access to so many luxuries we would consider basic necessities don't exist. These scientists have done a lot of work to show that a simple, effective solution can help people now. Not some time later when the next generation has enough to be able to use it.

This is something like a mosquito net. Cheap, easy to distribute, and shockingly effective against malaria. Personally, I like the laser solution more, but you can't deny helping people now for a more ideal solution later.

The trick, as always, is to also get the better solution later. And things like this centrifuge help! People have access to more advanced medical techniques and data than they had before. They'll get diagnosed sooner and more accurately. The next generation will be healthier, more energetic, and more optimistic about their chances at a longer life. They'll have more strength and will for the hard task of building up their home and country, and in a generation or two will be on their way to things like reliable power grids, communication infrastructure, transport, and more.

But they'll need things to help bootstrap them first. Iodine for clean water and paper centrifuges for diagnostics are just a few of the first steps for people who have so little modern riches are useless to them. It only took us a few generations to get here, and I bet they bootstrap faster and harder than anything we've seen, like so much of the Asian peoples.

Re: Paper Centrifuge

#50
post #9

Earlier quoted context omitted.

I can't remember using it to centrifuge blood samples, but maybe your childhood was different from mine.

We used it to demonstrate centrifugal forces in elementary school by spinning one and putting drops of food coloring in the center. They were made of lightly-waxed parchment paper so you could see a trail it left behind as it got flung off. I'm just surprised it took this long. That particular lesson was... 26 years ago for me.

Well why didn't you tell the world about this 26 years ago. Heck, why didn't you tell the world 2 days ago?
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