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Not necessarily. I've read from several who have successfully replaced Photoshop with The GIMP. (I've done this, though I still do photo work in LR). Inkscape has come a long way, and there are multiple, competing (and very competent) Lightroom replacements for digital darkroom work. I don't know how fleshed out the DTP side of things are but as a amateur photographer and graphic designer I've been able to get away w…
Anyone whose workflow is InDesign-heavy or Illustrator-heavy is shit out of luck, though; there is no reasonable replacement for either, and especially not for InDesign.
If you want to make books profesionaly there is no replacement for indesign. Scribus doesnt have multiline paragraph composing. So technicaly if you want to set something to the block, you will get always better result in indesign. 3D and photography are interesting to programmers but books... they make them with TeX. But with tex its hard to do columns and more complicated composition. One way could be scribus latex render windows but its somehow shitty.
Its too niche thing i guess.
Same goes for After Effects - node based composing is fine on linux but layer based for animation (motion graphics). AE only thing on the planet.
Its getting frustrating especialy with recent decline of mac os and mac hw. Again - hackintosh to the rescue but try to find hackintosh laptop.