Earlier quoted context omitted.
Eh, not really. It's not getting to altitude that's expensive, it's speed. Orbit is blisteringly fast.
It's a lot easier to get up to speed if you don't have to deal with cutting through a heavy chunk of atmosphere on the way up. Plus, rocket designs could vary, be less concerned about aerodynamics, if they were starting from a launch platform already in very thin air. A wider, shorter rocket might work better in thin air, for example, but that would be impractical launching from sea-level as is tradition.
I know it'll never happen for a variety of reasons. But it's such a cool plane and when you think about cruising at mach 3 (2000mph+, 15% of escape velocity (http://www.sr-71.org/blackbird/sr-71/)) it seems like it could make the rocket equation for a plane-launched rocket much, much more forgiving.