Earlier quoted context omitted.
Yah, this can make an overwhelming difference in the long run. I used to drive semi-regularly between Wisconsin and Minnesota, a stretch of about 280 miles; others in my family would make the same trip with the same car during the same times of year, and my mileage per tank was always significantly different, and we couldn't figure out why initially. Turns out they used cruise control for most of the stretch, which I…
For clarity, did cruise control produce better or worse mpg figures?
Cruise control was significantly worse than driving it normally, at least when I was at the wheel.
The route is a very hilly one, so I somewhat suspect it's that the cruise control was not very good at knowing when to accelerate and when to coast.