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23andme for only $99 today only

23andme.com

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Re: 23andme for only $99 today only

#61
post #31

Can anyone tell me if this comparison is pretty accurate? http://www.decodeme.com/product-comparison Seems like the snp coverage is a lot lower (green = 23andme).

Mike Cariaso, who does SNPedia (http://www.snpedia.com/index.php/SNPedia), and knows what he is talking about, says that 23andme offers the best SNP/$ ratio of the DTC providers

Re: 23andme for only $99 today only

#63
post #59

Earlier quoted context omitted.

Just to give you an example, I just bought at an auction the complete contents of a defunct company. Amongst the stuff I got was their servers and their bookkeeping. I never entered in to any agreement with the people whose data is stored on those servers, and yet I have all of it. A 'survival clause' that would guarantee destruction of your data in case the company goes out of business would be a minimum here. But i…

I'd argue that this is what makes 23andme interesting. Without that capability, it's a toy for rich people. First of all, today, this is not full genome information, just your genotype. Second, if we want good molecular medicine, information like this is essential (some might argue the only way) to get good sampling and do the appropriate research. Addendum since I can't reply to the comment. They don't quite have th…

> this is not full genome information, just your genotype.

That's what they give you. But you give them your full genome.

Re: 23andme for only $99 today only

#65

Earlier quoted context omitted.

Your DNA is half your parents', and your childrens DNA is half yours. Given a sufficiently large number of datapoints you can work out the DNA of those in between. And given a few 'confirmed' identities you could use that more complete picture to work out the identities of the rest, even if you did not know their names. Your DNA is your identity. It just hasn't been tied to the meta data of your name, address and soc…

In a far off future, where enough DNA data is publicly (!) available, that may be the case. Until then, to which data set should any company compare my DNA to find out who I am?

23andme is collecting data at a fair rate, there are other companies like them. Pooling the data between all those companies is going to allow you to fill in a bunch of 'blanks'. At some point that will reach critical mass and you can map the remainder.

I'm not good enough at math to give you the percentage of a certain population in order to be able to infer the rest, maybe someone else here can do that.

But given a population size 'n' if you get a random distribution of individuals and you know their genes and you know have a graph of relationships (say through facebook or some other means of tracing links between people) you should be able to make a formula that tells you what kind of 'coverage' you can expect based on how large a sample.

Re: 23andme for only $99 today only

#68

Send your $99 to me. I'll pick a disease at random and you likely have a better, if not, as good a chance at getting it based on how they calculate risks. Today only, I'll do it for $9.

This is only upvote worthy if it's premise is true. For that, we need evidence.

Re: 23andme for only $99 today only

#69
post #42

Earlier quoted context omitted.

Wouldn't they be tied to the agreement that you had when you signed up for the data? I always thought that you'd have to agree with new "terms-of-use" whenever they change

Just to give you an example, I just bought at an auction the complete contents of a defunct company. Amongst the stuff I got was their servers and their bookkeeping. I never entered in to any agreement with the people whose data is stored on those servers, and yet I have all of it. A 'survival clause' that would guarantee destruction of your data in case the company goes out of business would be a minimum here. But i…

The potential upside of this type of research is worth the risk of loss of anonymity. I would post my genome to a public website if it would help advance medical science.

[Disclosure: I participated in public health genomics research in grad school.]

Re: 23andme for only $99 today only

#70
post #32

Earlier quoted context omitted.

I'd like to hear from those that wouldn't do this. What are your reasons for not trusting this site?

Well, today they're 23andme, arguably in fairly rough waters (which is probably the reason for this promotion in the first place). Tomorrow they could be sold to the highest bidder, who might not feel they were bound to the terms of service of their predecessor. It could be an insurance company, for instance. And based on your name, your genetic data and a whole bunch of other factors they might decide to deny you or…

Remember that one of the key investors is Sergey Brin, so "Don't be evil" would apply to 23andMe. Sergey is married to the co-founder of 23andMe, Anne Wojcicki.
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