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Anti-Aging Startup Raises $116M With Bezos Backing

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Re: Anti-Aging Startup Raises $116M With Bezos Backing

#201

Post by anexprogrammer »

ryuker16 wrote: post #182
matt_wulfeck wrote: post #89

Earlier quoted context omitted.

Thankfully death comes along and sorts through the wants from the willing. It has a nice way of making space for a newer generation of thinkers. Old prejudices die, new thinkers arrive. There's nothing wrong with your thinking. In my humble opinion it shows your personal desires without much concern for everyone else. I guess this is the rub I get from most people that extol the Silicon Valley dream of extending the…

I'd imagine a society with 200 yr old people would be much wiser and sanely run.

Perhaps. There might be a lot more cynicism and conservatism. Our legislators might not have adjusted to the implications of telephone and tv, let alone apps and online privacy.

Oh, I see. You mean we should be able to run on to 200 don't you? ;)

Re: Anti-Aging Startup Raises $116M With Bezos Backing

#202

Post by Peaker »

eagsalazar2 wrote: post #187

Humans should not be immortal like gods until they attain godlike control of their impulse to consume and reproduce. If we get total liberation from nature's constraints (already 90% there), without evolving a corresponding ability to plan and resource long term, it will make the ecological disaster we're already witnessing 1000X worse and we'll likely destroy ourselves anyway. I'm not saying death doesn't suck or th…

Population-size wise, everyone living forever is like adding two children on average to each family.

Since people will still die from various causes and diseases, it'll be less.

Re: Anti-Aging Startup Raises $116M With Bezos Backing

#203

Post by stickfigure »

Frogolocalypse wrote: post #153
pointytrees wrote: post #65

Earlier quoted context omitted.

I sometimes talk about wanting to live forever and get weird stares. Are you joking me?? I want to hike every trail in the world. I want to climb every mountain. I want to play every video game. I want to beat the hardest raids in every expansion of WoW. I want to learn multiple langauges. I want to spend several years living in every biome. I want to learn all of the programming languages. I want to go back to schoo…

> I want to climb every mountain. Statistically speaking, anti-aging isn't going to be the defining factor in your mortality, if that's what you want to do with your extended lifetime.

I'm disappointed that this isn't the top-rated response, because I think it's totally fair. The parent post resonated with me incredibly -- I want to do all the things. Yes, I fully expect to die in a motorcycle accident far from modern health care. I'm ok with that. I suspect the parent would agree.

"I f*cked up spectacularly" is an acceptable way to go. "I watched a lot of TV" is not. 80 years is not long enough to attempt all the spectacular things.

Re: Anti-Aging Startup Raises $116M With Bezos Backing

#204

Post by anexprogrammer »

a13n wrote: post #56

I'm not a billionaire and I'm not old, but I am so excited about anti-aging. I know Hacker News is super negative, but who doesn't want to live longer?! Of all the pain points humans experience, you'd think death lies pretty high on the list. Why are people fighting this?

Some aspects of living longer I'd love to have - more experiences, more knowledge and so forth.

If we achieve this, but don't reduce input, longer life will just mean we live to see the crash. So in order to have long life how can we stop the growth, and ideally reduce, the human population without totalitarian approaches?

Before solving aging we need to solve achieving a genuinely sustainable number for the planet and its biosphere.

Re: Anti-Aging Startup Raises $116M With Bezos Backing

#205

Post by hohenheim »

eagsalazar2 wrote: post #187

Humans should not be immortal like gods until they attain godlike control of their impulse to consume and reproduce. If we get total liberation from nature's constraints (already 90% there), without evolving a corresponding ability to plan and resource long term, it will make the ecological disaster we're already witnessing 1000X worse and we'll likely destroy ourselves anyway. I'm not saying death doesn't suck or th…

Not only it is taxing on planet earth I think there is more to it. Assume people of middle ages lived 1000 years longer than they did, I doubt the civilization on earth would have developed as far as it did.

To progress we need people to die and the new to born with radical ideas.

Re: Anti-Aging Startup Raises $116M With Bezos Backing

#206

Post by PetoU »

meerkats1 wrote: post #8

I would love to get involved with a company like this, however I am only a software engineer with no background in the biological sciences. Is there a feasible path that does not involve going back to school for many years? I am not afraid of learning new things or doing the hard work I'd need to do, I just feel like that route would be highly inefficient. I would really like to contribute towards meaningfully extend…

same for me. Doing CRUD apps is fine, but how can I apply that in biotech ?

Re: Anti-Aging Startup Raises $116M With Bezos Backing

#207

Post by tudorw »

eagsalazar2 wrote: post #187

Humans should not be immortal like gods until they attain godlike control of their impulse to consume and reproduce. If we get total liberation from nature's constraints (already 90% there), without evolving a corresponding ability to plan and resource long term, it will make the ecological disaster we're already witnessing 1000X worse and we'll likely destroy ourselves anyway. I'm not saying death doesn't suck or th…

does death suck ? I've never tried it, personally I find life has it's downsides, so to fear something I've never tried seems irrational ? I like children, and old people, if the old people don't get going at some point, where do we put the children?

Re: Anti-Aging Startup Raises $116M With Bezos Backing

#208

Post by danieltillett »

eagsalazar2 wrote: post #187

Humans should not be immortal like gods until they attain godlike control of their impulse to consume and reproduce. If we get total liberation from nature's constraints (already 90% there), without evolving a corresponding ability to plan and resource long term, it will make the ecological disaster we're already witnessing 1000X worse and we'll likely destroy ourselves anyway. I'm not saying death doesn't suck or th…

Ending aging won't make humans immortal. Humans will still die in car crashes, suicides, murders, bath slips, etc. All ending aging will do is stop us from dying slowly by decrepitude.

Life expectancy without aging is something like 550 years [1] - not my idea of immortality.

1. https://www.reddit.com/r/theydidthemath/comments/33hs0d/requ...

Re: Anti-Aging Startup Raises $116M With Bezos Backing

#209

Post by danieltillett »

reasonattlm wrote: post #45

Some things to look at when thinking about the plausibility of senescent cell clearance as a rejuvenation therapy. 1) 25% median life extension in mice: http://dx.doi.org/10.1038/nature16932 2) Reverses aspects of lung tissue aging in mice, including loss of elasticity: http://insight.jci.org/articles/view/87732?key=a306472a4316d... 3) The missing link in diabetic retinopathy: http://dx.doi.org/10.1126/scitranslmed.a…

You are right on the mechanism, wrong on the solution. The problem is that senescent cells (aging) are an evolved response to prevent cancer - basically aging is an anti-oncogenic system. Remove the senescent cells and you will die of cancer at a young age.

Aging and cancer are tightly intertwined and you can't cure aging without first curing cancer.

Re: Anti-Aging Startup Raises $116M With Bezos Backing

#210

Post by drcross »

hohenheim wrote: post #205
eagsalazar2 wrote: post #187

Humans should not be immortal like gods until they attain godlike control of their impulse to consume and reproduce. If we get total liberation from nature's constraints (already 90% there), without evolving a corresponding ability to plan and resource long term, it will make the ecological disaster we're already witnessing 1000X worse and we'll likely destroy ourselves anyway. I'm not saying death doesn't suck or th…

Not only it is taxing on planet earth I think there is more to it. Assume people of middle ages lived 1000 years longer than they did, I doubt the civilization on earth would have developed as far as it did. To progress we need people to die and the new to born with radical ideas.

That's a fairly large assumption. Students need 24 years of education to get to Phd level before they reach the state of the art and push things forward. If we lived longer with augmented brain power we would have more experts in fields and thus more progress. My assertion isn't any less refutable than yours.
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