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Anti-Aging Startup Raises $116M With Bezos Backing

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Re: Anti-Aging Startup Raises $116M With Bezos Backing

#151

Post by solipsism »

atomical wrote: post #149
matt_wulfeck wrote: post #89

Earlier quoted context omitted.

Thankfully death comes along and sorts through the wants from the willing. It has a nice way of making space for a newer generation of thinkers. Old prejudices die, new thinkers arrive. There's nothing wrong with your thinking. In my humble opinion it shows your personal desires without much concern for everyone else. I guess this is the rub I get from most people that extol the Silicon Valley dream of extending the…

You sound like a nihilist, except for the part about appearing to have "concern for everyone else."

You say that like it's an insult. And nihilists don't necessarily not have concern for others.

Re: Anti-Aging Startup Raises $116M With Bezos Backing

#152

Post by solipsism »

rezashirazian wrote: post #122
komali2 wrote: post #53

Earlier quoted context omitted.

I don't understand this belief, can you expand on it? The way I see it, you don't "lose" anything when you die, because a "loss" implies the lack of ability to use something you once were able to use, and the feeling that comes from that lacking. When someone dies they'll never again be able to use stuff, so there is no loss.

I think we agree up to "a 'loss' implies the lack of ability to use something you once were able to use". Since a dead person is unable to do anything, being a billionaire or not leads to the same conclusion. Where we differ is on the feeling that comes from that lacking. A dead person feels nothing and by your definition is not losing anything since they can't feel it. this is all very true and I agree, however as h…

You think, when billionaires think about death, that they're bemoaning the loss of their money? That's a very strange thing to believe, and I'm very sure it's wrong.

Re: Anti-Aging Startup Raises $116M With Bezos Backing

#153

Post by Frogolocalypse »

pointytrees wrote: post #65
a13n wrote: post #56

I'm not a billionaire and I'm not old, but I am so excited about anti-aging. I know Hacker News is super negative, but who doesn't want to live longer?! Of all the pain points humans experience, you'd think death lies pretty high on the list. Why are people fighting this?

I sometimes talk about wanting to live forever and get weird stares. Are you joking me?? I want to hike every trail in the world. I want to climb every mountain. I want to play every video game. I want to beat the hardest raids in every expansion of WoW. I want to learn multiple langauges. I want to spend several years living in every biome. I want to learn all of the programming languages. I want to go back to schoo…

> I want to climb every mountain.

Statistically speaking, anti-aging isn't going to be the defining factor in your mortality, if that's what you want to do with your extended lifetime.

Re: Anti-Aging Startup Raises $116M With Bezos Backing

#154

Post by Frogolocalypse »

solipsism wrote: post #151
atomical wrote: post #149

Earlier quoted context omitted.

You sound like a nihilist, except for the part about appearing to have "concern for everyone else."

You say that like it's an insult. And nihilists don't necessarily not have concern for others.

Yes. Nihilist != Narcissist.

Re: Anti-Aging Startup Raises $116M With Bezos Backing

#155

Post by megablast »

pointytrees wrote: post #65
a13n wrote: post #56

I'm not a billionaire and I'm not old, but I am so excited about anti-aging. I know Hacker News is super negative, but who doesn't want to live longer?! Of all the pain points humans experience, you'd think death lies pretty high on the list. Why are people fighting this?

I sometimes talk about wanting to live forever and get weird stares. Are you joking me?? I want to hike every trail in the world. I want to climb every mountain. I want to play every video game. I want to beat the hardest raids in every expansion of WoW. I want to learn multiple langauges. I want to spend several years living in every biome. I want to learn all of the programming languages. I want to go back to schoo…

Do you want to all that with a depleted body and will?

Re: Anti-Aging Startup Raises $116M With Bezos Backing

#156

Post by pointytrees »

Frogolocalypse wrote: post #153
pointytrees wrote: post #65

Earlier quoted context omitted.

I sometimes talk about wanting to live forever and get weird stares. Are you joking me?? I want to hike every trail in the world. I want to climb every mountain. I want to play every video game. I want to beat the hardest raids in every expansion of WoW. I want to learn multiple langauges. I want to spend several years living in every biome. I want to learn all of the programming languages. I want to go back to schoo…

> I want to climb every mountain. Statistically speaking, anti-aging isn't going to be the defining factor in your mortality, if that's what you want to do with your extended lifetime.

Hah, yea, good point. Honestly though, I live in northern California, and I have climbed a good handful of the 10k peaks around here, but there are just so many more I have not had the time to visit. So many parts of the Pacific Crest Trail that I havn't been able to hike. And that's just stuff in a 2 hour drive. I've climbed a few dozen of the Tahoe peaks, but there are so many more to do. Over the past few years, I've probably gotten to a mountain top once every 4 weeks. Some months I go every weekend, other months I get busy with other things. I never want to do Everest. But, there are some 14k in Denver that might be fun. Believe me, I'll hike more trails and mountains than most people, but there are just so many hikes, and not enough weekends.

Re: Anti-Aging Startup Raises $116M With Bezos Backing

#157

Post by CuriouslyC »

reasonattlm wrote: post #45

Some things to look at when thinking about the plausibility of senescent cell clearance as a rejuvenation therapy. 1) 25% median life extension in mice: http://dx.doi.org/10.1038/nature16932 2) Reverses aspects of lung tissue aging in mice, including loss of elasticity: http://insight.jci.org/articles/view/87732?key=a306472a4316d... 3) The missing link in diabetic retinopathy: http://dx.doi.org/10.1126/scitranslmed.a…

Seems like exposure to mild stressors would be a good way to cause senescent cells to go apoptotic. Calorie restriction, exercise, hypoxia, heat shock, etc.

Re: Anti-Aging Startup Raises $116M With Bezos Backing

#158

Post by Frogolocalypse »

pointytrees wrote: post #156
Frogolocalypse wrote: post #153

Earlier quoted context omitted.

> I want to climb every mountain. Statistically speaking, anti-aging isn't going to be the defining factor in your mortality, if that's what you want to do with your extended lifetime.

Hah, yea, good point. Honestly though, I live in northern California, and I have climbed a good handful of the 10k peaks around here, but there are just so many more I have not had the time to visit. So many parts of the Pacific Crest Trail that I havn't been able to hike. And that's just stuff in a 2 hour drive. I've climbed a few dozen of the Tahoe peaks, but there are so many more to do. Over the past few years, I…

Obligatory meme.

https://pbs.twimg.com/media/CkCVg49VEAE-zku.jpg

Re: Anti-Aging Startup Raises $116M With Bezos Backing

#159

Post by pointytrees »

nullc wrote: post #111
pointytrees wrote: post #65

Earlier quoted context omitted.

I sometimes talk about wanting to live forever and get weird stares. Are you joking me?? I want to hike every trail in the world. I want to climb every mountain. I want to play every video game. I want to beat the hardest raids in every expansion of WoW. I want to learn multiple langauges. I want to spend several years living in every biome. I want to learn all of the programming languages. I want to go back to schoo…

I've found it helpful to share this with people: http://www.nickbostrom.com/fable/dragon.html

At first I thought the article was going to explain why it isn't worth pursuing agelessness, but I'm impressed at how well it wrapped everything up. Great article, thanks.

Re: Anti-Aging Startup Raises $116M With Bezos Backing

#160

Post by pointytrees »

BjoernKW wrote: post #75
pointytrees wrote: post #65

Earlier quoted context omitted.

I sometimes talk about wanting to live forever and get weird stares. Are you joking me?? I want to hike every trail in the world. I want to climb every mountain. I want to play every video game. I want to beat the hardest raids in every expansion of WoW. I want to learn multiple langauges. I want to spend several years living in every biome. I want to learn all of the programming languages. I want to go back to schoo…

Not enough time? Perhaps, but forever is a long time. Quite possibly it's exactly our limited time that has us achieve great things. If you have all the time in the world why bother starting that business or learning that new skill today? Might as well start tomorrow ... I also find it at least a bit disturbing that WoW is so high on that list. Then again, if you have all the time in the world ...

The items were not listed in order. I've had a couple spins of playing WoW and DotA, and often times the reason I quit are because there are so many other things I want to do. I work full time, I have a rental property, I have a small business (with my wife), 1 dog, 3 cats, no kids yet, but soon hopefully. We get outdoors, go camping, visit family. Probably getting into sailing next summer. Life's great. Don't get me wrong. But, dang. With "forever" I could get so much done. I'm also fairly patient, and conservative, so with time on my side, the safest investments will pay off well. But, then again, if you have time to work, why not jump into the risky investments. If you lose everything, you can just rebuild. Maybe a hybrid of both approaches. However, if death were cured, then money, investing, and finance would probably change quite radically as well.

I love thinking about this concept. I hope that over the next 20 years, they figure out how to extend life to 125 years, so that then in the following 20-40 years they can extend life indefinitely. Here's to hoping.

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