Earlier quoted context omitted.
I was involved with a research effort to predict certain cell biology features via molecular dynamics simulations between 2003 and 2006. It's what I wrote my thesis on. After school was done and my research group's grant ran out I started writing software for a living instead of looking for another research position. I still keep up with molecular and biological simulation research efforts because it's intrinsically…
This has been my main objection to brain inside of a computer thinking. If we could simulate the universe inside of a computer we could do all kinds of neat things, such as drug development in a computer, but it isn't algorithmically possible. The Kurzweillians are just assuming that we'll wave the magic wand and have efficient algorithms for everything such that computer simulation of reality will be trivial. If you…
So basically I agree with you: there's no generic march-of-progress that assures a world of Kurzweillian wonders. I want to see more concrete evidence of progress in relevant areas before I start entertaining life after the Singularity. (I expect a future profoundly shaped by many "narrow" AIs rather than AGI precisely because there has been so much concrete progress with the former compared to the latter.)