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Nootropics

gwern.net

301–310 of 404 posts

Re: Nootropics

#301

Earlier quoted context omitted.

> and also a 1.5 to 2 hour intense weightlifting workout (primarily focused on your thighs/legs[1][2], since they are the biggest muscles. being nitpicky here but we shouldn't be promoting "time in the gym" as a measurement of a workout's success. frankly, if you're doing an "intense" workout for "2 hours" something's wrong.

"Intense" here means lifting weights close to the maximum you can lift for certain number of repetitions. This kind of workout can easily take 1.5 to 2 hours, and IMHO qualifies as intense.

If you are actually following set, repetition and rest period guidelines it should probably take quite a bit less, depending on how many exercises you can fit in. Since I never seem to be able to hit the 30 second rest period between sets, and I can't always get to the machine I want immediately after my last exercise because it's in use, I always seemed to average 10-15 minutes an exercise. I haven't been to the gym in months though. :/

Re: Nootropics

#302

So you're telling me you alter your biochemistry to become more productive without a care for how it affects your overall (mostly mental) health? Hell, I started smoking cigarettes at 16, which I rank near the top of my worst decisions ever, despite the fact that it helped me hack my brain chemistry as I powered through numerous difficult math and CS classes with top scores. As a result, I spent years thrashing, kick…

> that many people (men, in particular) say their greatest regret was working so hard i think many people also regret not working harder.

Also, "working hard" is pretty meaningless without context, especially if we're going to talk about regretting it.

For example, carving out some time at night for your side projects that might pay your rent one day vs. staying longer at work to get a leg up on imminent deadlines that were too aggressive vs. working hard to be Employee of the Month vs. working hard to learn programming.

Re: Nootropics

#303

A shame no info on testosterone - that's the one I'm most interested in both from physical and psychological perspective, I know a few people who used it but they are in physical/service jobs, I wonder how it would affect programming productivity. Any throwaways here willing to share their experiences ?

I've also been self-prescribing testosterone for years, dosage ranging from 200mg/week to 3,000mg/week. I find the sweet spot to be around 200mg-500mg/week. Anything higher makes me lethargic, at 3000mg/week I would sleep 15 hours and get almost nothing done, of course at 3000mg the physical results were dramatic. I could sit on my ass and eat a gallon of ice cream all day and still lose body fat. In my experience negative effects are most prominent when there is fluctuations of hormone levels, such as when changing the dosage dramatically. Of course it isn't a magic drug, the effects are slow and gradual. How it will affect programming productivity, I would say is subjective, but it will give you an overall better sense of well being.

Re: Nootropics

#304
post #127

Earlier quoted context omitted.

"It's hard for me to fall asleep. I haven't cracked it yet how to do it perfectly. What helps: view the problem as improving your likelihood to sleep. Before I viewed the problem as falling asleep 100% of the time, which is a really defeating view to have when I can't fall asleep." I did not respond to your sibling comment who speaks of anxiety. It sounds like a real pathology and something I have no business general…

Also on the weight lifting / sleep connection, in 4 hr Body, Time Ferris states: TAX THE NERVOUS SYSTEM WITH ISO-LATERAL MOVEMENTS. Exercise is commonly recommended to improve sleep. The problem for me was that results were unpredictable. I might exercise for 20 minutes and fall asleep in 10 minutes, or I might exercise for two hours and fall asleep in two hours. There was no repeatable cause and effect. It seemed li…

This is really interesting, I have hard time dealing with sleep since moving abroad, break-up, far from family, isolated small city. Before I could bet with someone that I can fall asleep in less that 5 minutes.

Now, I've done it all and nothing seem to help:

  - tried medicine(benzodiazepam family, ugly stuff, addictive, stopped after just 1 week, fuck the doctor that prescribed this)
  - tried removing everything with a lot of caffeine, everything in the vegetable world has it, impossible to eliminate, but no more: coffee, tea, sugary drinks
  - adapter water drinking to maximum needed
  - running 15 minutes HIIT style(4 minutes at 12.5 km/h, 1 minute 16 km/h, repeat)
  - weightlifting for the rest 45 minutes - every day session
  - meditation (stoping the mind, have a single thought, mandalas, matras, yantras ...)
  - no lcd, led light before 23:00, no more tv before bed
  - went back to the doctor, best clinic for this in Europe... got prescribed mirtazapine, anti-depresant, helps but the side effects are weired and dehumanizing(taking 1/4 of 30 mg pill, far below the reference amount that they say it has any effect)
  - sleep settled to 5 h / d, not bad, but not perfect
  - mirtazapine gave me a very long face in the morning, looking destroyed, feeling rested and calm, but face dropped, looking like droopy dog
  - went back to doctor, started CBT, bought books on CBT, personal opinion: pile of crap(and I was very opened to them)                    
  - f**k the doctor again(I trust doctors, not this one), he asked me money and go to have treatment at home, told me I am normal, not like the people in the waiting room
  - tried melantonin, calming teas, etc etc, bullshit, money wates
  - made a girlfriend, sex helps, but when you have it until 03:00 AM due to "crazy" girlfriend, prefer the pills
  - broke up, back to 5 h sleep
  - back to doctor
  - recommended me THC, a liquid version, helped a bit but too expensive
  - started smoking weed, cheaper, fuck lungs, need to sleep
  - helped a lot for the first months until I became addicted without noticing(addiction is not easy to describe, that is why everybody seems to share a different opinion, bullshit, you become addicted of smoking to be normal, not for the high)
  - had to unlearn the weed, waves of heat and cold and sleepless nights followed, catastrophic, need my freedom back, even with 4-5 h of sleep, don't want to depend on anything foreign of my body
  - went back home, slept like a rock for the first days, next days awful, unstoppable mind
  - back to computer programming until I get tired
  - back to reading books until I collapse into sleep
  - I collapse but then I wake up at 03:00 am if I start sleeping at 01:00
  - change bed place/orientation(mythology of European people), helped a bit, but don't know if it is real or wishful thinking
Effects(personal) of lack of sleep over cognition:

  - my mind still solves complex problems(I am a programmer), but the speed lacks to be desired
  - entering the zone is almost impossible
  - my hands feel like they have 3 tons when I lift them from desk
  - I still love what I am doing
  - If I find a challenge that is impossible to solve in one day work I get a bad mood
  - bad mood gets solved upon second day
Even with all these, I still love life at maximum, would want to achieve and do more, but not whatever the costs, not becoming addicted of foreign stuff!

Guys, be grateful for your lives and go out and speak with people, one day this magic substance might be found, but I am more convinced that it will come from machine/human merger that from substances. Good or bad, that is the most likely future.

Re: Nootropics

#305

Earlier quoted context omitted.

Try listening to podcasts. It completely cured my inability to get to sleep. In fact, there are podcasts aimed directly at people like you (and me): http://www.sleepwithmepodcast.com/ Some other 'sleep favourites' of mine would be Skeptoid, Lore, Dan Carlin's Hardcore History, 99% invisible. Give it a try. I use the Stitcher app and set the timer to turn off streaming at the end of an episode. I'm usually asleep with…

I tried a few episodes of sleep with me, and it creeped me right the hell out. It was some guy talking in a pouty, condescending baby-voice about some nonsense or other. His voice especially threw me off. Dan Carlin is great, but way too intense and interesting for me to sleep to. I pay attention to the podcast and want to hear "just another 20 minutes" instead. 99% invisible is perfect in this regard. Roman has a gr…

Have you tried Max Richter's "Sleep"? http://pitchfork.com/reviews/albums/20987-sleep/

Re: Nootropics

#307

Zoloft I am afraid of sounding like a shill, but the fact is I'm 30 engineer, who has been trying to feel better my whole life through experiments with: ketamine, CBD, various nutrients, various dietary changes, exercise, being more social, meditation. None of them made lasting improvement like sertraline has, I wish I had been open-minded enough to try it years ago. In retrospect, maybe it was ridiculous to try to f…

How you deal with Zoloft killing your libido?

It came back in about 6 weeks for me. Never had any issues after that.

Re: Nootropics

#308

The best nootropic is getting a good nights sleep. It takes effort! Preparing for bed early and disciplining yourself to put the light out is not easy. Not nearly as easy as popping a pill. But it's so much more effective than any drug listed here. And for a safe and provable quick cognitive boost, take some caffeine, preferable green tea with theanine.

It's hard for me to fall asleep. I haven't cracked it yet how to do it perfectly. What helps: view the problem as improving your likelihood to sleep. Before I viewed the problem as falling asleep 100% of the time, which is a really defeating view to have when I can't fall asleep. Sleep tips that help me: 1. meditation: still experimenting with body-scan vs. breath meditation, they both help but have different effects…

Look up Delayed sleep phase disorder. It's basically night owl syndrome. The two things that have some evidence for their usage are melatonin and SAD lights.

Re: Nootropics

#309

Right now, there are people in the nootropic community who are using experimental compounds that haven't yet passed clinical trials and in some cases have no prior history of human use at all. A large portion of the data used by communities like this (even "self-experimenters") -- use cargo cult pseudo-science to justify their drug use -- something that can go horribly wrong in inexperienced hands. The majority of th…

While individuals that are ignorant, lazy, cheap, and impatient exist in all communities, Gwern(the author) does not possess any of those qualities. He is probably one of the least lazy, ignorant, and impatient people I have read online.(I didn't mention cheap because his writing doesn't give me any illumination into his spending habits)

Re: Nootropics

#310

Earlier quoted context omitted.

"Intense" here means lifting weights close to the maximum you can lift for certain number of repetitions. This kind of workout can easily take 1.5 to 2 hours, and IMHO qualifies as intense.

If you are actually following set, repetition and rest period guidelines it should probably take quite a bit less, depending on how many exercises you can fit in. Since I never seem to be able to hit the 30 second rest period between sets, and I can't always get to the machine I want immediately after my last exercise because it's in use, I always seemed to average 10-15 minutes an exercise. I haven't been to the gym…

3-5 minute rest periods are not unusual at heavy weights, although I personally try to keep it to two minutes to save time. With warm-up sets and some waiting for equipment I often find myself spending 1.5 hours at the gym. Super setting would help a lot but it's impractical at most gyms :(
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