Earlier quoted context omitted.
Perhaps try Doctors Without Borders? It is more of a long-term kind of travel, but you will be doing real good and definitely living an adventure. They need people with all kinds of backgrounds, not just medical, so it might be worth a look.
As a simpler, less ambitious adventure, suitable for people that don't want to quit their job, you might try Habitat for Humanity. There are international builds where you travel somewhere and work on building homes in areas where there isn't adequate low-income housing. You get to meet and work with locals for a couple of weeks. I went to rural Hungry. I had one friend who also went on the build. He talked me into d…
I highly advise against this. There is no shortage of unqualified labor in underdeveloped countries. Most of these projects are just 'feel good charity tourism'.
If you want to make a difference you are much better of donating 20% of a US salary which will employ many more underqualified locals who actually need the job.