Tiff? That is a format I haven't heard in a long time. edit: to everyone replying. TIFF is awful. We have lossless compression now (read PNG) which is at least a billion times better. We shouldn't use it for anything in this day and age. Hell, just DEFLATE your TIFF and call it a new format. It will be better than TIFF
This is very helpful for processing which treats each pixel as a sample of the scene, such as computational microscopy or remote sensing. I've always wondered if that had something to do with why it was hosted at remotesensing.org.