Earlier quoted context omitted.
They aren't super sized, but between the C-17 and C-5, the US has ~250 large cargo planes in service. There's also hundreds of 747s that could be pressed into service (or just utilized) in a world gone to hell scenario.
I don't think of it as a "world gone to hell scenario" so much as a "World War II scenario" or a "Bronze Age collapse scenario". Smaller cargo planes should be somewhat more survivable than bigger ones in an environment full of Angels' Teeth and other micro-drones, but downing 250 large cargo planes still only requires landing 250 small robots on them and cutting a fuel line or something.
I suppose I could have more clearly stated that I was arguing that the US is already leaning on large aircraft strategically, it wouldn't be a shift.