I know from personal experience the sub-title to this article is "How I'm justifying a bad decision". Entrepreneurs know when they're making a bad decision, whether consciously or not. [Edited for brevity. No disrespect, but hate to see a Developer give up on their independence]
Joining a larger organization can provide the opportunity to accomplish things that would be difficult or impossible on your own. And if it doesn't work out, or eventually becomes disappointing, it's still possible to hop back on the entrepreneurial horse and ride off into the sunset.