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Fasting triggers stem cell regeneration of damaged, old immune system (2014)

news.usc.edu

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Re: Fasting triggers stem cell regeneration of damaged, old immune system (2014)

#81

I fasted for a day when fighting with my parents. Worst thing to do since I am a Type-1 diabetic and ended up with Diabetic Ketoacidosis the next day and a near-death experience :-( Fasting is not for everyone!

Well it's pretty much for any mammal except type-1 diabetics --- plus folks taking medication for blood sugar / insulin regulation without informing themselves thoroughly beforehand and monitoring carefully.

Re: Fasting triggers stem cell regeneration of damaged, old immune system (2014)

#82
post #15

Earlier quoted context omitted.

About 3 years ago, I undertook a water fast that lasted about 17 days. It does take a lot of mental preparation. Nutrition wise, I ate only fruits for about a week before the fast. The first few days were very hard, but then I simply did not feel hunger at all. I intended to continue the fast for 30 days. But from about the 4th day onwards my mouth started having an awful odour and my tongue had a thick white coating…

That odour is probably the ketones coming into play when the body starts using fat for energy, instead of carbs or protein. And yes, it's a well known fact.

For 3 weeks straight would be unusual though and not explain the commonly occurring tongue coating.

Re: Fasting triggers stem cell regeneration of damaged, old immune system (2014)

#83

Earlier quoted context omitted.

I regularly fast for 20+ hours (calorie restriction, I do drink water because I am not an idiot) once or twice a week. You get very used to it. While its not something I look forward to, it's purely psychological. A few hours after I miss 'breakfast' my tummy rumbles two or three times and then my body doesn't care anymore. The max time I've fasted is forty hours and I have to say if you can get past the first fours…

How is a 500-600 calorie meal 'very small'? Most normal dinners are 600-800 calories.

If you're used to 800, 500 is a pretty huge drop.

My intake to maintain weight is about 2600kcal/day as a lightly-moderately active person. I normally do a breakfast of about 400-500 calories, and then 900-1000 for lunch and dinner. So if I weren't just waking up, 500-600 would be very small for me.

Re: Fasting triggers stem cell regeneration of damaged, old immune system (2014)

#84
post #45

Earlier quoted context omitted.

> Some people have a lot of "bad stuff" which will enter their bloodstream when their body breaks down adipose for fuel. [...] you'll have severe "detox" symptoms a day or two into the fast. Your body doesn't work that way. "Detoxing diets" are pure superstition – which toxins are those supposed to be anyway? From [1]: "The 'toxins' usually remain undefined, with little to no evidence of toxic accumulation in the pat…

"Toxicological Function of Adipose Tissue: Focus on Persistent Organic Pollutants" http://ehp.niehs.nih.gov/wp-content/uploads/121/2/ehp.120548... "The studies discussed here indicate that AT (Adipose tissue) plays a central role in POP (persistent organic pollutants) toxicology. This role is complex and may seem paradoxical. Indeed, there is evidence that AT is protective under conditions of acute or subacute exposu…

It is very annoying when people dismiss anything sounding vaguely like "alternative therapy" out of fear of quackery. I remember reading a comment on Reddit where someone denied there the body ever contains any toxins... apparently they were not familiar that the liver and kidneys have a purpose.

Re: Fasting triggers stem cell regeneration of damaged, old immune system (2014)

#85
post #17

I tried searching for the original article, but this is the closest I could find that had a better writeup than from the telegraph: https://news.usc.edu/63669/fasting-triggers-stem-cell-regene... This is the most relevant summary: "In both mice and a Phase 1 human clinical trial involving patients receiving chemotherapy, long periods of not eating significantly lowered white blood cell counts. In mice, fasting cycles…

> I'll pass on this intermittent fasting "fad" for now! It's amazing how people are prone to experiment with this type of things. They're willing to undergo a very unpleasant experience because it might (unlikely) give them a (slight) health improvement.

I think when someone has cancer, a slight health improvement is big enough.

Furthermore, people experiment with all kinds of things for slight health improvements to stay healthy. Working out is not the most pleasant experience when you think about it, but it becomes pleasant because you mentally associate it with something positive and there are traces of euphoria kicking in when it's a pretty intense workout.

Most people work out to lose weight when it's been years I've told anyone who asked me that for weight loss, working out is more tiring and less effective "calorifically" than simply not eating that extra piece of pie. I've seen people want to lose weight, go for a 20 minute run, then come back and down all kinds of food and still hoping/believing/thinking they're going in the right direction for weight loss and they're eating to recover from the effort.

An Olympic swimmer might need 4,000 calories daily. Most of us don't.

Re: Fasting triggers stem cell regeneration of damaged, old immune system (2014)

#86

In my own experience day 3 of a water fast had profound effect on my health. I have some health issues so I closely monitor my blood pressure and blood sugar. On the morning of the fourth day my blood pressure and blood sugar would drop tremendously and stay normal for several months. ymmv

It should be noted that going from eating a lot of unhealthy food to a 24hr fast might be a little on the dangerous side for some.

The first time I tried it after about 12 or so hours I felt like I was going to pass out. So I ate something to stablize myself. After eating healthier for a while it's much easier to attempt.

Re: Fasting triggers stem cell regeneration of damaged, old immune system (2014)

#87

In my own experience day 3 of a water fast had profound effect on my health. I have some health issues so I closely monitor my blood pressure and blood sugar. On the morning of the fourth day my blood pressure and blood sugar would drop tremendously and stay normal for several months. ymmv

We are missing a lot of context - much of which you can't supply here even if you wanted to. For example, it seems entirely plausible and not exactly rocket science that not eating the wrong foods (for a given person - what "wrong" means may vary widely and wildly depending on their context!) is better than eating it. For an example (of the example), if you eat a lot of high glycemic index foods it's not hard to gues…

You are right on every point. Water fasting was not Dr. recommended but the profound positive effects were documented by the follow on tests they performed. No one seems to know why it "worked". I dunno if it is knowable at this point. But one thing I do know I was very ill and now I'm a lot better and fasting was a key reason why.

Re: Fasting triggers stem cell regeneration of damaged, old immune system (2014)

#88
post #38

Earlier quoted context omitted.

You didn't consume anything but water for five consecutive days? I also don't undertake what you mean by, "I wasn't very toxic."

> You didn't consume anything but water for five consecutive days? Unpleasant at first but not dangerous to healthy individuals. As someone pointed out: if we wasn't capable of doing that we would likely have been extinct long ago.

TIL. I am not very knowledgable about the human limits of consumption, so this was pretty surprising to me.

Re: Fasting triggers stem cell regeneration of damaged, old immune system (2014)

#89
post #38

Earlier quoted context omitted.

You didn't consume anything but water for five consecutive days? I also don't undertake what you mean by, "I wasn't very toxic."

Yea. It was fairly uneventful. The first day or two I was hungry, but it was mild. Perhaps it was easy, as my eating habits left me naturally in intermittent fasting mode (I'd eat lunch at 1pm, dinner at 8pm, then nothing else).

Do you find that you drink more water to try and "stifle" the hunger?
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