A dear friend of mine quit smoking, cold-turkey, and she went completely berserk for 3 months, with dangerous mood swings and outbursts of violence. She had previously suffered a mild depression, which now emerged as some kind of dark nightmare of rage and guilt and hatred and also self-hatred.
This is what struck me: of all the SSRIs she'd had ever tried, none had ever worked as well as tobacco. Tobacco moderated her depression and mood swings more effectively than any modern drug that her doctors had prescribed for her.
So I when I read this passage, what strikes me is how much truth there is still in this, even in the year 2016:
"its virtues rarely get a hearing, and yet the latter are many and great. To quiet nervous rest; to soothe a ruffled temper; to favour calm and partial thought; to steady and clear (not to cloud) a confused, overworked brain; "