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A Medical Mystery of the Best Kind: Major Diseases Are in Decline

nytimes.com

131–140 of 152 posts

Re: A Medical Mystery of the Best Kind: Major Diseases Are in Decline

#131
post #110

Earlier quoted context omitted.

That isn'y evolution if it is epigenetic, it would be another type of adaption, Lamarckian really: https://en.wikipedia.org/wiki/Lamarckism#Epigenetic_Lamarcki...

This is incorrect. Evolution is simply change over generations by natural selection. the mechanism by which that happens, be it DNA or epigenetics or whatever, is not strict

Yes/no... It has to be heritable beyond a single reproductive cycle. Which isn't the case with all epi markers.

Re: A Medical Mystery of the Best Kind: Major Diseases Are in Decline

#132
post #119

Earlier quoted context omitted.

> Autism - Depression, ADD, and similar disorders My personal impression is that the rise of mental conditions is an increase in diagnosis, not occurrence. An awful lot of people who, just a few decades ago, would have been dismissed as lazy, stupid, whiny, or the all-purpose "crazy" are actually starting to receive recognition and treatment. That's a good thing.

> My personal impression is that the rise of mental conditions is an increase in diagnosis, not occurrence Do you have a source for this? It goes against much I've read myself recently—for instance, depression has strong links to inflammation—perhaps shitty diets and no exercise are catching up to people.

The problem with some of these conditions unfortunately is that it is only possible to speculate based on behavioral reports, because the term simply didn't exist back then (or if it did, it existed in widely varying terms describing some sort of "insanity" or "neurosis"). So unfortunately I don't think there is an answer to this question.

In reading up on the histories of various classical composers, for instance, several of them appear to have suffered regularly from depressive orders (a very definitive example is Sergei Rachmaninoff). A few of them such as Erik Satie and Anton Bruckner appear to be afflicted with what we now know as OCD. Can we definitively diagnose, though? No, we only have reports to go off of.

Heck, we're still pretty fuzzy with the diagnosis and root cause of some of these mental conditions now. (See: the definition of Aspergers)

Re: A Medical Mystery of the Best Kind: Major Diseases Are in Decline

#133

Earlier quoted context omitted.

I'd heard that the most violent areas in New Orleans are those with high concentrations of lead in the environment, and a quick Google search brought up this piece from February that states that precisely: http://www.motherjones.com/environment/2016/02/lead-exposure...

Couldn't that be correlation as well? That is - those neighborhoods are the least likely to be rehabilitated and the buildings retrofitted to remove pollutants?

Yes, but unlike for pure correlation we actually have a mechanism that could explain it. So it isn't on the level of "all we have is correlation", but of course it also isn't on the level of "we know for sure".

Re: A Medical Mystery of the Best Kind: Major Diseases Are in Decline

#135

Earlier quoted context omitted.

I would imagine a global smoking increase statistic would be per-capita as well but without a citation we won't know.

"In his own studies of smoking, Stebbins has shown how the tobacco industry has turned to markets in the developing worl to make up for loss in sales first in the United States and subsequently in parts of the European market. Governments in developing nations often do not have the ability to limit tobacco marketing and, usually in need of financial help, they are open to introducing taxable commodities to their citi…

This is an area where I see the free market causing great harm. How can a population contend with greedy, money-rich corporations who wage huge psychological and legal campaigns? It's very one-sided. In the US, science and the people's own best interest are seldom enough. The government must have some balance of power to regulate corporations that are otherwise happy to abuse their fellow humans and distort culture and consciousness to systematically disempower whole populations.

It's an awful cycle. It's possible that a system built on nurturance and development, one that empowered people with a wide array of tools including compassion and self-realization, would produce corporate leaders who could themselves balance multiple constructive ends. Imagine if the mega-corps who routinely disenfranchise poor communities and third world countries not only sought money and power, growth and impact, but also felt internally compelled to be accountable, admit mistakes, build constructive non-manipulative and non-bullying relationships, empower others when possible, and respect others when not possible even when taking care of oneself, etc.

I'm a big fan of free-will and independence and no human having more authority than another, but I also see a huge importance in nurturing and developing children to bear those responsibilities constructively, for example free from low self esteem and arrogance, and rich with curiousity, support networks, courage and inventiveneess. Unfortunately, nurturing, developing and supporting others are tasks that are largely seen as "feminine" and therefore economically unimportant (stay at home parents are free labor, and teachers, nannies, etc earn very little money, and research in those areas is similarly seen as lesser science to math and engineering). These professions are often shunned by those needing to defend their "masculinity", and in fact nurturance and emotional support is often required of women and people of color as free labor (the classic "mother" and "grandmother" and "POC friend" role). So it's a strange world we live in, where corporations are seen as people under the law, and are of course directed by people in charge, and yet we keep the bar very low for how mature and capable these people-corporations are.

Re: A Medical Mystery of the Best Kind: Major Diseases Are in Decline

#137
post #121

Earlier quoted context omitted.

Clinically speaking, perhaps biological evolution had a chance of dealing with this. Now, biological evolution has been replaced by "social evolution". A trait of physically debilitating condition, that is treatable, is no longer a reproduction fullstop. Those genes carry on. What genes will peter out are the absence of skills that are employable and not being able to find a partner because of that. Of course this is…

Unemployed people have plenty of kids. Not sure what's being selected for, but it's not that

>Not sure what's being selected for

Latex allergy

Re: A Medical Mystery of the Best Kind: Major Diseases Are in Decline

#138

Earlier quoted context omitted.

I would imagine a global smoking increase statistic would be per-capita as well but without a citation we won't know.

"In his own studies of smoking, Stebbins has shown how the tobacco industry has turned to markets in the developing worl to make up for loss in sales first in the United States and subsequently in parts of the European market. Governments in developing nations often do not have the ability to limit tobacco marketing and, usually in need of financial help, they are open to introducing taxable commodities to their citi…

That's a photo, of a rate of growth, two decades and half ago.

At least in Brazil, smoking rate is much lower than what it was by then.

Re: A Medical Mystery of the Best Kind: Major Diseases Are in Decline

#139

Earlier quoted context omitted.

> Autism - Depression, ADD, and similar disorders My personal impression is that the rise of mental conditions is an increase in diagnosis, not occurrence. An awful lot of people who, just a few decades ago, would have been dismissed as lazy, stupid, whiny, or the all-purpose "crazy" are actually starting to receive recognition and treatment. That's a good thing.

The increase in suicide rates seems to be evidence against this hypothesis.

Isn't there a connection between anti-depressants and suicide? Basically they give you enough energy to get going, but not enough to break the depression so you have just enough to go and kill yourself.

Basically, you have to watch someone like a hawk when they first go on antidepressants until they get over the hurdle and start feeling good again.

Re: A Medical Mystery of the Best Kind: Major Diseases Are in Decline

#140

Earlier quoted context omitted.

A comment like this could be very insightful, but you didn't mention what h-pylori is, or why water treatments help reduce it.

The cool thing about the internet is there's a whole universe of information at your fingertips: https://en.wikipedia.org/wiki/Helicobacter_pylori

I read an blog entry by a retired surgeon. He said when he started a lot of his bread and butter business was surgically fixing ulcers. Then came drugs to reduce stomach acid, followed by the discovery of Helicobacter pylori, and that business mostly went away.
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