I think the average programmer makes many more mistakes due to not knowing computer science and math / lacking a deep understanding of programming than due to any other deficiency like not knowing laws. It is at least true for the programmers I've worked with and have not been satisfied with.
So in the real world, this is what causes me problems - actual problems with a large application that cause friction with clients - people being bad at programming and not knowing even the most basic computer science and math, mostly manifesting itself in the application becoming littered with inefficient code over time (the second most common problem being lack of or superficial technical knowledge, such as using a framework or even language without understanding how it works under the hood, this usually manifests itself in the same way).
Note that the "I don't need to know math/cs" people will often not realize they needed something because they will just solve the problem incorrectly, inefficiently, or decide it is not possible to solve efficiently and compromise on requirements. What's worse, even if they are shown the error of their ways multiple times, they almost never truly change their mind, regardless of evidence. It is a mindset people seem to commit to early in their career, or even to a more general version of the same mindset in childhood, and never change it. That's why there's so many of them.
Sure, there might be situations where it is not useful to be a better programmer than you are. But I would say that is not the norm. I don't work on some algorithmically-super-complex application, it is just a typical large application used by professionals for their work; it doesn't involve any truly difficult problems but has a huge number of relatively small and easy problems all over the place. I'd say it's somewhere in the middle of the software development spectrum.