Hacker News Board Hacker News, browsed like a classic message board
Live data from Hacker News

Fasting-like Diet Reduces Multiple Sclerosis Symptoms

neuroscientistnews.com

Post reply on HN
Print view View original

31–40 of 40 posts

Re: Fasting-like Diet Reduces Multiple Sclerosis Symptoms

#31

Post by easytiger »

j-pb wrote: post #26
tkyjonathan wrote: post #19

The Swank diet and later the McDougall diet have been halting and sometimes slightly regressing MS symptoms in most cases, for decades now. The Swank diet in particular, has kept people alive with the disease for 34 years. https://www.youtube.com/watch?v=kZ5NGLM1k90

> The Swank diet in particular, has kept people alive with the disease for 34 years. It's not an achievement to keep people with MS alive. People with MS have an average life expectancy that is very close to that of healthy people (literature varies between a couple of months http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1069023/ and several years, with 7 being the highest that I've seen http://www.nationalmssociety.or…

Also a highly varied disease that can have almost no effects vs almost immediately chronic ones.

Re: Fasting-like Diet Reduces Multiple Sclerosis Symptoms

#32

Post by j-pb »

easytiger wrote: post #31
j-pb wrote: post #26

Earlier quoted context omitted.

> The Swank diet in particular, has kept people alive with the disease for 34 years. It's not an achievement to keep people with MS alive. People with MS have an average life expectancy that is very close to that of healthy people (literature varies between a couple of months http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1069023/ and several years, with 7 being the highest that I've seen http://www.nationalmssociety.or…

Also a highly varied disease that can have almost no effects vs almost immediately chronic ones.

Yeah the spectrum is huge, however disease progression is also hard to predict, so a person with some very heavy relapses at onset might be relapse free for years afterwards and vice versa.

Iirc though there are some studies that showed that progression is in general more benign than initially estimated in most cases.

Re: Fasting-like Diet Reduces Multiple Sclerosis Symptoms

#33

Post by kaoD »

nikolay wrote: post #29
nikolay wrote: post #10

Food is so yesterday!

Why all the downvotes? You can't handle a joke?! So pathetic!

Jokes are usually frowned upon in Hacker News. It keeps the conversation focused and meaningful instead of derailing into chains of puns à la Reddit.

It's not that the community can't handle a joke, it's just trying to avoid the slippery slope. There are other places for more lighthearted discussion.

Mentioning downvotes is also frowned upon.

Disclaimer: I didn't downvote you, just explaining.

Re: Fasting-like Diet Reduces Multiple Sclerosis Symptoms

#34

Post by nikolay »

kaoD wrote: post #33
nikolay wrote: post #29

Earlier quoted context omitted.

Why all the downvotes? You can't handle a joke?! So pathetic!

Jokes are usually frowned upon in Hacker News. It keeps the conversation focused and meaningful instead of derailing into chains of puns à la Reddit. It's not that the community can't handle a joke, it's just trying to avoid the slippery slope. There are other places for more lighthearted discussion. Mentioning downvotes is also frowned upon. Disclaimer: I didn't downvote you, just explaining.

On the contrary - unsubstantiated, silent, cowardly downvotes turn HN into Reddit.

And my comment was both a joke and a serious statement. As with everything, you need to find the golden mean, and people today are overeating their way into chronic disease!

We don't need as much food and as quality food as we think. In fact, fasting outweighs careful food selection as you can't go wrong with fasting, but you could and eventually would by following conflicting and ever-changing dietary guidelines.

There is much wisdom in my single short sentence!

But I start to think that the audience here is incapable of reading between the lines, which is sad given the HN claims for superior intelligence. In fact, the San Fran crowd is addicted to food, and based on my personal experience here; it goes postal when you dare to say something against their questionable eating habits!

Re: Fasting-like Diet Reduces Multiple Sclerosis Symptoms

#35

Post by joveian »

biot wrote: post #18
ams6110 wrote: post #4

What is a "fasting-like" diet? It is presumably not absolute fasting otherwise no need for the "like" qualifier.

From the paper [0]: "Modified human fasting mimicking diet. A single cycle of the modified fasting mimicking diet consist of Day 1 – pre-fasting followed by Day 2-8 – very low calorie diet. Day 1-prefasting consists of an 800 kcal (about 40% of normal caloric intake similar to mouse Day1 FMD) monodiet (fruit, rice, or potatoes) by preference of individuals. On the following day patients were recommended to use an ora…

If this is a real effect, I wonder how many calories a persona can eat and still get the fasting effect. I have a non-24 hour circadian rhythm (although some thing still seem synchronized to light), which causes all sorts of negative effects, and I have found that eating Also interesting is that I have had some severe digestive issues for years; antibiotics helped for a month or two and eating about 3000 kcal over five days has been just as helpful for a couple of weeks now and seems likely to be at least as effective as the antibiotics. However, one or two days of calorie restriction does not have that effect on me. If this fasting result holds for MS, the effect of fasting on gut bacteria could potentially be part of how it works.

Re: Fasting-like Diet Reduces Multiple Sclerosis Symptoms

#36

Post by jdpigeon »

dualogy wrote: post #13
ams6110 wrote: post #4

What is a "fasting-like" diet? It is presumably not absolute fasting otherwise no need for the "like" qualifier.

Technically a fast-mimicking diet would be: ad-libitum fat, barely sufficient protein (such that protein recycling is maintained --- no idea how to calculate this individually), near-zero (ie. only trace) carbohydrate. I suppose zero protein would most mimick fasting if done for just a few weeks tops but once all degenerate/damaged/mutated/malfunctioning proteins have been degraded for protein recycling or gluconeoge…

Well, that sounds just like a ketogenic diet. They actually investigate keto alongside their fasting diet and find similar benefits in many areas, just not to as large a degree.

Re: Fasting-like Diet Reduces Multiple Sclerosis Symptoms

#37

Post by aruggirello »

biot wrote: post #18
ams6110 wrote: post #4

What is a "fasting-like" diet? It is presumably not absolute fasting otherwise no need for the "like" qualifier.

From the paper [0]: "Modified human fasting mimicking diet. A single cycle of the modified fasting mimicking diet consist of Day 1 – pre-fasting followed by Day 2-8 – very low calorie diet. Day 1-prefasting consists of an 800 kcal (about 40% of normal caloric intake similar to mouse Day1 FMD) monodiet (fruit, rice, or potatoes) by preference of individuals. On the following day patients were recommended to use an ora…

Oddly enough, Natrum Sulphuricum seems to be a homeopathic remedy, not a common laxative - can anybody shed some light on this?

Re: Fasting-like Diet Reduces Multiple Sclerosis Symptoms

#38

Post by feklar »

geocar wrote: post #16
ams6110 wrote: post #4

What is a "fasting-like" diet? It is presumably not absolute fasting otherwise no need for the "like" qualifier.

No. It's not absolute fasting, although I do that some times. I've been doing alternate-day fasting or a 3/5 diet, for around 6-8 months at a time, for the last several years because it makes me feel better . There was a great program on the BBC[1] about "fasting-like diets", which generally consist of extreme caloric restriction for some time -- where what counts as "extreme" and "some time" varies from programme to…

There was an HN story months ago about a study touting the benefits of a 5 day low cal fast every X months and a startup formed by the researchers is now shipping products based on it http://aboutprolon.com/

Re: Fasting-like Diet Reduces Multiple Sclerosis Symptoms

#39

Post by JamieAli »

Losing weight is 80% diet and 20% exercise, there's no point in doing hours and hours of cardio and weight training if you're still eating junk food, because you will not lose any weight, sure you may get fitter but you won't lose any fat.

Also, if you can't fit 30 minutes of cardio in a day, 7 minutes will do the trick tremendously, well that's only if you're doing 7 minutes of HIIT (High Intensity).

Do at least a 20 second sprint then a 20 second run, alternate for 7 minutes, everyday, you will feel great and revitalized after.

Be careful in which guides you follow, there are TONS of fad diets and lies. Here's a great weight loss program I used to lose weight and permanently keep it off: http://thehealthspecialists.com

Re: Fasting-like Diet Reduces Multiple Sclerosis Symptoms

#40

Post by ludamad »

biot wrote: post #18
ams6110 wrote: post #4

What is a "fasting-like" diet? It is presumably not absolute fasting otherwise no need for the "like" qualifier.

From the paper [0]: "Modified human fasting mimicking diet. A single cycle of the modified fasting mimicking diet consist of Day 1 – pre-fasting followed by Day 2-8 – very low calorie diet. Day 1-prefasting consists of an 800 kcal (about 40% of normal caloric intake similar to mouse Day1 FMD) monodiet (fruit, rice, or potatoes) by preference of individuals. On the following day patients were recommended to use an ora…

Why the enema?
Post reply on HN