Does it mean that protein intake should be lowered to reduce cancer risk?
No.
How cancer cells fuel their growth
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Re: How cancer cells fuel their growth
#12It's a good study from high quality researchers, but to be fair there is a study almost every week for the last 50 years saying something like this.
References please?
Re: How cancer cells fuel their growth
#13Re: How cancer cells fuel their growth
#14Very interesting. What does this mean for low carb, high protein diets heavily promoted these days (Keto)? Reminds me of this talk on TED - William Li, Anti-Angiogenesis therapy: https://www.youtube.com/watch?v=OjkzfeJz66o Does this research mean these diets and therapies are less effective than previously thought?
The effect is probably small
The body is very efficient at turning protein and fat into energy
However the issue with proteins/amino-acids is that the body actually needs them and can't convert carbs or fats into them (you actually need some of the amino-acids).
Maybe the cure is to limit your protein intake but that poses other problems
Re: How cancer cells fuel their growth
#15Very interesting. What does this mean for low carb, high protein diets heavily promoted these days (Keto)? Reminds me of this talk on TED - William Li, Anti-Angiogenesis therapy: https://www.youtube.com/watch?v=OjkzfeJz66o Does this research mean these diets and therapies are less effective than previously thought?
This is not my area of expertise by any means, but wouldn't this assume that cancer would grow proportional to the amount of fuel available? Normal cells certainly don't operate this way.
Re: How cancer cells fuel their growth
#16thought the answer to the headline was going to be -- "with venture capitalist dollar"
Re: How cancer cells fuel their growth
#17thought the answer to the headline was going to be -- "with venture capitalist dollar"
thought the answer to the headline was going to be -- "with venture capitalist dollars"
Re: How cancer cells fuel their growth
#18Very interesting. What does this mean for low carb, high protein diets heavily promoted these days (Keto)? Reminds me of this talk on TED - William Li, Anti-Angiogenesis therapy: https://www.youtube.com/watch?v=OjkzfeJz66o Does this research mean these diets and therapies are less effective than previously thought?
The Warburg effect is a metabolic pathway involving anaerobic burning of glucose. When cells consume fats instead of sugar it must be aerobically. Burning glucose aerobically is much more efficient than doing so without O2.
The belief is that this means that low carb diets should be a good preventative for cancers as they remove the metabolic pathway needed by the cancer cells as there isn't enough glucose for them.
EDIT: Here is an article that goes into this in a bit more depth: http://eatingacademy.com/nutrition/way-exploit-metabolic-qui...
Re: How cancer cells fuel their growth
#19Very interesting. What does this mean for low carb, high protein diets heavily promoted these days (Keto)? Reminds me of this talk on TED - William Li, Anti-Angiogenesis therapy: https://www.youtube.com/watch?v=OjkzfeJz66o Does this research mean these diets and therapies are less effective than previously thought?
Not much - they use amino acids as building blocks. Still ferment glucose for energy.
Re: How cancer cells fuel their growth
#20Very interesting. What does this mean for low carb, high protein diets heavily promoted these days (Keto)? Reminds me of this talk on TED - William Li, Anti-Angiogenesis therapy: https://www.youtube.com/watch?v=OjkzfeJz66o Does this research mean these diets and therapies are less effective than previously thought?
I believe most of these diets promote low carb, high fat, moderate protein. In general consuming more protein than needed for cellular maintenance does little good and gets converted to energy through additional steps; since it's easier to get energy from carbs or fat it makes sense to consume only enough protein, not less, not more.