Earlier quoted context omitted.
s/crazy chick/crazy dude/ Having a partner of either sex that also suffers mental illness (perhaps more severely than you do) can exacerbate un-healthy or unhelpful ways of thinking. I don't think the writer was placing entire blame with the partner, but actually making a good point earlier about the psychological reinforcement from being around them
I read it as light humour. The tone of that line is very much in keeping with his humorous points in past writings (and code). I don't know Kenneth but I've read enough of his writing to recognise his style. I genuinely believe the grandparent is doing Kenneth a disservice here.
It's cool that you recognize his voice, but if this article takes off because of its interdisciplinary nature, it is likely to get an audience that isn't composed exclusively of people who know his style.