How is "subtract a, 3" better than "a-3"? I can already feel my carpal tunnel acting up!
I actually don't consider Mu to be a language. (I'm the author.) It's a low-level starting point to explore ways to make the standard OS primitives more testable. I don't need it to look nice. Higher level languages can come later, once the foundations are in place.
I actually am growing increasingly suspicious of all our navel-gazing about syntax. We spend all our time in places like HN thinking about how to make small screenfuls of code look nice, but all that effort hasn't really translated into helping me understand the large-scale structure of random open-source codebases more easily.
Perhaps one way to think about it is that syntax helps insiders keep a codebase in their head. I'm more concerned with ways to help more outsiders import a codebase in the first place. Because people leave and move on, and it's very hard for software projects today to improve once their original authors move on. More on this: http://akkartik.name/post/readable-bad
(I'm susceptible to carpal tunnel, but it hasn't become a bigger issue. I take wrist breaks.)
[1] I can even imagine doing the translation in machine code, so that Mu then becomes self-hosting without needing any of the current stack. I might go down that road..