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The brain functional connectome is robustly altered by lack of sleep

ncbi.nlm.nih.gov

31–40 of 74 posts

Re: The brain functional connectome is robustly altered by lack of sleep

#31
post #26

Earlier quoted context omitted.

At what time do you take the magnesium?

Shouldn't you be asking your doctor that? And also whether you, particularly, should take such a supplement?

I know this will be an unpopular opinion but Magnesium is conventional enough of a supplement that you can easily get away with trying it on your own without consulting a physician.

Re: The brain functional connectome is robustly altered by lack of sleep

#32
post #6

Earlier quoted context omitted.

I have never slept well my entire life. 4-6 hours a night is my average. It doesn't seem to impact me... I have always felt great, and I have always coded on complicated things without issue. There has to be a ratio difference for people.

Same here. In fact, when I sleep for 8-9 hours, I am profoundly less sharp and productive. That said, I'm only 20, and I don't want to wreak havoc on my future health. Difficult stuff.

Have a large glass of water before sleep (real water, no soda or juice). A lot of issues and tiredness after long sleep is caused by dehydration.

Re: The brain functional connectome is robustly altered by lack of sleep

#33
post #32
post #6

Earlier quoted context omitted.

Same here. In fact, when I sleep for 8-9 hours, I am profoundly less sharp and productive. That said, I'm only 20, and I don't want to wreak havoc on my future health. Difficult stuff.

Have a large glass of water before sleep (real water, no soda or juice). A lot of issues and tiredness after long sleep is caused by dehydration.

Sadly I don't think that's the case for me. I drink too much water if anything.

Re: The brain functional connectome is robustly altered by lack of sleep

#34
post #26

Earlier quoted context omitted.

At what time do you take the magnesium?

Shouldn't you be asking your doctor that? And also whether you, particularly, should take such a supplement?

do you consult your doctor before trying a different brand of coffee?

Re: The brain functional connectome is robustly altered by lack of sleep

#35
post #9

I have had sleep issues for many years. I have seen sleep specialists regarding this issue. They basically tell you to reduce stress. But my daily life is not particularly stressful. But my job as a software developer involves brain-intensive work, and when I come home after work, I work on hobby software development projects, which means my brain is working intensely whenever I am awake. That may be the stress leadi…

What sleep issues did you have exactly? There are many, and magnesium supplementation may not be suitable for all. Thanks in advance.

Some days I wake up after only a couple of hours of sleep. Other days my brain simply won't turn off. I try to sleep, but the brain simply won't stop thinking random stuff and staying awake.

Re: The brain functional connectome is robustly altered by lack of sleep

#36
post #34
post #26

Earlier quoted context omitted.

Shouldn't you be asking your doctor that? And also whether you, particularly, should take such a supplement?

do you consult your doctor before trying a different brand of coffee?

If merely trying a new brand can cause a medical condition worthy of its own name or if it can have adverse effects depending on other medical issues I might have, then yes: https://en.wikipedia.org/wiki/Hypermagnesemia

Do you take all kinds of vitamins and supplements with this cavalier, throw caution to the wind, attitude, or just magnesium because you happen to know it's tame enough? Before supplements don't always bode well with existing conditions, or even with high dosages.

Re: The brain functional connectome is robustly altered by lack of sleep

#37
post #23

With an AHI[1] of [148, 150] across two tests, I'm quite sure my brain is... shall we say.. "uniquely connected". // I just spent the last few days in the ICU due to the heart problems that come from lack of O2. Not fun. Seriously, get your sleep. [1] https://en.wikipedia.org/wiki/Apnea%E2%80%93hypopnea_index

That sounds extremely unpleasant. What can you do about it, and what are you managing to do?

Re: The brain functional connectome is robustly altered by lack of sleep

#38
post #2

Barely suppressing my horror at the word 'connectome' to make a relevant comment: As a new (6 months) parent, I can confirm anecdotally that lack of sleep profoundly messes with the brain. Even getting your normal duration of sleep, but punctuated with lots of short waking periods, makes it almost impossible to function in highly demanding intellectual tasks for any length of time. And if you have any underlying ment…

For better or worse, 'connectome' is a legit term used in the field. It's relatively newish (quickly skimming the literature, first mention was in a 2005 article). It follows the naming convention setup by 'genome', and includes many variants: - genome (set of dna material in a cell) - exome (set of exonic dna material) - transcriptome (set of all messenger RNA) - proteome (set of proteins in a cell) - interactome (s…

Yep, it is, and "functional" means undirected in this context, as contrasted w/ "effective" or directed. These graphs are often defined by stats like Granger causality as well as some partition of the brain.

There's a Prof. named Sporns who has a lot to say about this.

Re: The brain functional connectome is robustly altered by lack of sleep

#39
post #36
post #34

Earlier quoted context omitted.

do you consult your doctor before trying a different brand of coffee?

If merely trying a new brand can cause a medical condition worthy of its own name or if it can have adverse effects depending on other medical issues I might have, then yes: https://en.wikipedia.org/wiki/Hypermagnesemia Do you take all kinds of vitamins and supplements with this cavalier, throw caution to the wind, attitude, or just magnesium because you happen to know it's tame enough? Before supplements don't alway…

there are instant coffee brands with extra caffeine added in as well... you can die from drinking the previous quantity of this new brand of coffee!

Re: The brain functional connectome is robustly altered by lack of sleep

#40
post #9

I have had sleep issues for many years. I have seen sleep specialists regarding this issue. They basically tell you to reduce stress. But my daily life is not particularly stressful. But my job as a software developer involves brain-intensive work, and when I come home after work, I work on hobby software development projects, which means my brain is working intensely whenever I am awake. That may be the stress leadi…

How many days before significant changes appeared ?
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