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The brain functional connectome is robustly altered by lack of sleep

ncbi.nlm.nih.gov

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Re: The brain functional connectome is robustly altered by lack of sleep

#12
post #9

I have had sleep issues for many years. I have seen sleep specialists regarding this issue. They basically tell you to reduce stress. But my daily life is not particularly stressful. But my job as a software developer involves brain-intensive work, and when I come home after work, I work on hobby software development projects, which means my brain is working intensely whenever I am awake. That may be the stress leadi…

Alright, you convinced me. Sounds very similar to my ongoing situation.

I've been taking clonidine and vitamin d for stress and anxiety and I'm really annoyed with the way doctors prescribe (wrote about this a couple hours ago in this thread -https://news.ycombinator.com/item?id=10824879)

Was it a drastic change, or something more subtle for you?

Re: The brain functional connectome is robustly altered by lack of sleep

#13
post #9

I have had sleep issues for many years. I have seen sleep specialists regarding this issue. They basically tell you to reduce stress. But my daily life is not particularly stressful. But my job as a software developer involves brain-intensive work, and when I come home after work, I work on hobby software development projects, which means my brain is working intensely whenever I am awake. That may be the stress leadi…

Instead of working on software when you get home, how about zoning out to some TV or movies? I find that after an hour of TV, it is very easy to fall asleep.

I'd give this a try, because meds always have side effects.

Re: The brain functional connectome is robustly altered by lack of sleep

#15
post #9

I have had sleep issues for many years. I have seen sleep specialists regarding this issue. They basically tell you to reduce stress. But my daily life is not particularly stressful. But my job as a software developer involves brain-intensive work, and when I come home after work, I work on hobby software development projects, which means my brain is working intensely whenever I am awake. That may be the stress leadi…

Do you experience an increased vividness to dreams when taking magnesium supplements?

Re: The brain functional connectome is robustly altered by lack of sleep

#16
post #12
post #9

I have had sleep issues for many years. I have seen sleep specialists regarding this issue. They basically tell you to reduce stress. But my daily life is not particularly stressful. But my job as a software developer involves brain-intensive work, and when I come home after work, I work on hobby software development projects, which means my brain is working intensely whenever I am awake. That may be the stress leadi…

Alright, you convinced me. Sounds very similar to my ongoing situation. I've been taking clonidine and vitamin d for stress and anxiety and I'm really annoyed with the way doctors prescribe (wrote about this a couple hours ago in this thread - https://news.ycombinator.com/item?id=10824879 ) Was it a drastic change, or something more subtle for you?

It made a big difference for me. No, not subtle.

Re: The brain functional connectome is robustly altered by lack of sleep

#17
post #15
post #9

I have had sleep issues for many years. I have seen sleep specialists regarding this issue. They basically tell you to reduce stress. But my daily life is not particularly stressful. But my job as a software developer involves brain-intensive work, and when I come home after work, I work on hobby software development projects, which means my brain is working intensely whenever I am awake. That may be the stress leadi…

Do you experience an increased vividness to dreams when taking magnesium supplements?

Possibly, not sure. I don't think I dreamed much before taking magnesium.

Re: The brain functional connectome is robustly altered by lack of sleep

#19
post #2

Barely suppressing my horror at the word 'connectome' to make a relevant comment: As a new (6 months) parent, I can confirm anecdotally that lack of sleep profoundly messes with the brain. Even getting your normal duration of sleep, but punctuated with lots of short waking periods, makes it almost impossible to function in highly demanding intellectual tasks for any length of time. And if you have any underlying ment…

For better or worse, 'connectome' is a legit term used in the field. It's relatively newish (quickly skimming the literature, first mention was in a 2005 article). It follows the naming convention setup by 'genome', and includes many variants: - genome (set of dna material in a cell) - exome (set of exonic dna material) - transcriptome (set of all messenger RNA) - proteome (set of proteins in a cell) - interactome (s…

While we're all on the same team, there's also a distinction in the functional connectome (often as determined by fMRI) vs the structural one (determined by viral tracers and electron microscopy). Of course the goal is to see how the two relate. The one described in the article is functional.

Re: The brain functional connectome is robustly altered by lack of sleep

#20
post #9

I have had sleep issues for many years. I have seen sleep specialists regarding this issue. They basically tell you to reduce stress. But my daily life is not particularly stressful. But my job as a software developer involves brain-intensive work, and when I come home after work, I work on hobby software development projects, which means my brain is working intensely whenever I am awake. That may be the stress leadi…

I can second the opinion on Magnesium. Though, instead of magnesium L threonate, I used Magnesium malate. I have tried citrate and orotate forms and while they were both good, compared to malate the effect was mild. The malate form of magnesium had a better calming effect on the mind and muscles. Will try L threonate next time and see how it works.

https://examine.com/supplements/magnesium/

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