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The brain functional connectome is robustly altered by lack of sleep

ncbi.nlm.nih.gov

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Re: The brain functional connectome is robustly altered by lack of sleep

#2
Barely suppressing my horror at the word 'connectome' to make a relevant comment:

As a new (6 months) parent, I can confirm anecdotally that lack of sleep profoundly messes with the brain. Even getting your normal duration of sleep, but punctuated with lots of short waking periods, makes it almost impossible to function in highly demanding intellectual tasks for any length of time.

And if you have any underlying mental issues (hint: you do), you better believe those are coming to the surface when you've been chronically sleep deprived for 3 months.

Long story short: for the love of all that is good, sleep well. If there's something stopping you, find a way to get help or get away for a while so you can get some real sleep. The ability to think properly comes back remarkably quickly after a good sleep.

Re: The brain functional connectome is robustly altered by lack of sleep

#3
post #2

Barely suppressing my horror at the word 'connectome' to make a relevant comment: As a new (6 months) parent, I can confirm anecdotally that lack of sleep profoundly messes with the brain. Even getting your normal duration of sleep, but punctuated with lots of short waking periods, makes it almost impossible to function in highly demanding intellectual tasks for any length of time. And if you have any underlying ment…

I have never slept well my entire life. 4-6 hours a night is my average. It doesn't seem to impact me... I have always felt great, and I have always coded on complicated things without issue.

There has to be a ratio difference for people.

Re: The brain functional connectome is robustly altered by lack of sleep

#4
post #2

Barely suppressing my horror at the word 'connectome' to make a relevant comment: As a new (6 months) parent, I can confirm anecdotally that lack of sleep profoundly messes with the brain. Even getting your normal duration of sleep, but punctuated with lots of short waking periods, makes it almost impossible to function in highly demanding intellectual tasks for any length of time. And if you have any underlying ment…

I have never slept well my entire life. 4-6 hours a night is my average. It doesn't seem to impact me... I have always felt great, and I have always coded on complicated things without issue. There has to be a ratio difference for people.

yes, even I have observed this to be a phenomenon, I have seen people who sleep barely few hours a day but they are energetic and can solve tough problems and stuff like that.

Re: The brain functional connectome is robustly altered by lack of sleep

#5
post #2

Barely suppressing my horror at the word 'connectome' to make a relevant comment: As a new (6 months) parent, I can confirm anecdotally that lack of sleep profoundly messes with the brain. Even getting your normal duration of sleep, but punctuated with lots of short waking periods, makes it almost impossible to function in highly demanding intellectual tasks for any length of time. And if you have any underlying ment…

I have never slept well my entire life. 4-6 hours a night is my average. It doesn't seem to impact me... I have always felt great, and I have always coded on complicated things without issue. There has to be a ratio difference for people.

Sleeping little != sleeping poorly. I only sleep 5-6 hours in a normal night. But usually very restful (not fitful or waking up a lot) hours.

Re: The brain functional connectome is robustly altered by lack of sleep

#6
post #2

Barely suppressing my horror at the word 'connectome' to make a relevant comment: As a new (6 months) parent, I can confirm anecdotally that lack of sleep profoundly messes with the brain. Even getting your normal duration of sleep, but punctuated with lots of short waking periods, makes it almost impossible to function in highly demanding intellectual tasks for any length of time. And if you have any underlying ment…

I have never slept well my entire life. 4-6 hours a night is my average. It doesn't seem to impact me... I have always felt great, and I have always coded on complicated things without issue. There has to be a ratio difference for people.

Same here. In fact, when I sleep for 8-9 hours, I am profoundly less sharp and productive.

That said, I'm only 20, and I don't want to wreak havoc on my future health. Difficult stuff.

Re: The brain functional connectome is robustly altered by lack of sleep

#7
post #2

Barely suppressing my horror at the word 'connectome' to make a relevant comment: As a new (6 months) parent, I can confirm anecdotally that lack of sleep profoundly messes with the brain. Even getting your normal duration of sleep, but punctuated with lots of short waking periods, makes it almost impossible to function in highly demanding intellectual tasks for any length of time. And if you have any underlying ment…

For better or worse, 'connectome' is a legit term used in the field. It's relatively newish (quickly skimming the literature, first mention was in a 2005 article). It follows the naming convention setup by 'genome', and includes many variants:

- genome (set of dna material in a cell)

- exome (set of exonic dna material)

- transcriptome (set of all messenger RNA)

- proteome (set of proteins in a cell)

- interactome (set of all interactions in a cell -- protein, small molecular, etc)

- metabolome (set of all small molecular compounds / interactions in a sample)

- connectome (set of all connections in the brain -- e.g. a wiring diagram)

etc etc

Re: The brain functional connectome is robustly altered by lack of sleep

#9
I have had sleep issues for many years. I have seen sleep specialists regarding this issue. They basically tell you to reduce stress. But my daily life is not particularly stressful.

But my job as a software developer involves brain-intensive work, and when I come home after work, I work on hobby software development projects, which means my brain is working intensely whenever I am awake. That may be the stress leading to my sleep issues. But I can't give up my hobby.

All doctors want to do is put me on prescription pills for the rest of my life, and all of these prescription sleeping pills are addictive. So I have been avoiding prescription meds.

Then I discovered that magnesium supplements largely solves my problem. I hope this helps someone: If you have sleep issues try Magnesium L-Threonate. Magnesium fixed two issues for me: sleep and muscle stiffness.

Re: The brain functional connectome is robustly altered by lack of sleep

#10
post #2

Barely suppressing my horror at the word 'connectome' to make a relevant comment: As a new (6 months) parent, I can confirm anecdotally that lack of sleep profoundly messes with the brain. Even getting your normal duration of sleep, but punctuated with lots of short waking periods, makes it almost impossible to function in highly demanding intellectual tasks for any length of time. And if you have any underlying ment…

I have never slept well my entire life. 4-6 hours a night is my average. It doesn't seem to impact me... I have always felt great, and I have always coded on complicated things without issue. There has to be a ratio difference for people.

do you sleep during the day? When you sleep 4 hours for couple days straight do you wake up easily with no fuzzy head or anything like that?
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