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How Cocaine Changes the Brain

neurosciencenews.com

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Re: How Cocaine Changes the Brain

#11

Post by eru »

golergka wrote: post #6
rogeryu wrote: post #5

Good to know is that the first time you take cocaine, it works about 1000 times stronger than the natural drugs in your brain, and thus the natural highs you get. These are the normal highs you get when you score a goal in sports, when you get an A for your exam, when the girl or boy you like wants to kiss you etc. So the first time(s) you use cocaine, you get a high that's incredible. The second time, this effect is…

> So the first time(s) you use cocaine, you get a high that's incredible. The second time, this effect is about 100 times stronger than usual, so 10 times less strong than the first time. > Then you want to go back to that first unbelievable fantastic time, and take more. You may get at 200, but the more often you take it, the less the effect, and the stronger the craving for it. This is more or less how (this) addic…

From what I've heard, weed seems to work better after the first few tries.

Re: How Cocaine Changes the Brain

#12

Post by dsfsdfd »

jmnicolas wrote: post #10
rogeryu wrote: post #5

Good to know is that the first time you take cocaine, it works about 1000 times stronger than the natural drugs in your brain, and thus the natural highs you get. These are the normal highs you get when you score a goal in sports, when you get an A for your exam, when the girl or boy you like wants to kiss you etc. So the first time(s) you use cocaine, you get a high that's incredible. The second time, this effect is…

> These are the normal highs you get when you score a goal in sports, when you get an A for your exam, when the girl or boy you like wants to kiss you etc. I don't do drugs but I don't have "normal highs" either, except once, 20 years ago ... Sometimes I wonder if I'm normal.

I had a similar thing. imho: More than likely you are pushing your feelings away - it's a cognitive style. Try to listen to the physical sensations of everyday life, eating, talking, etc. Possibly get some therapy...

Re: How Cocaine Changes the Brain

#13

Post by djhn »

jmnicolas wrote: post #10
rogeryu wrote: post #5

Good to know is that the first time you take cocaine, it works about 1000 times stronger than the natural drugs in your brain, and thus the natural highs you get. These are the normal highs you get when you score a goal in sports, when you get an A for your exam, when the girl or boy you like wants to kiss you etc. So the first time(s) you use cocaine, you get a high that's incredible. The second time, this effect is…

> These are the normal highs you get when you score a goal in sports, when you get an A for your exam, when the girl or boy you like wants to kiss you etc. I don't do drugs but I don't have "normal highs" either, except once, 20 years ago ... Sometimes I wonder if I'm normal.

Anhedonia is the term.

It could be symptom of a range of disorders both mild and serious.

Re: How Cocaine Changes the Brain

#14

Post by dsfsdfd »

djhn wrote: post #13
jmnicolas wrote: post #10

Earlier quoted context omitted.

> These are the normal highs you get when you score a goal in sports, when you get an A for your exam, when the girl or boy you like wants to kiss you etc. I don't do drugs but I don't have "normal highs" either, except once, 20 years ago ... Sometimes I wonder if I'm normal.

Anhedonia is the term. It could be symptom of a range of disorders both mild and serious.

Or possibly Alexithymia

Re: How Cocaine Changes the Brain

#15

Post by golergka »

eru wrote: post #11
golergka wrote: post #6

Earlier quoted context omitted.

> So the first time(s) you use cocaine, you get a high that's incredible. The second time, this effect is about 100 times stronger than usual, so 10 times less strong than the first time. > Then you want to go back to that first unbelievable fantastic time, and take more. You may get at 200, but the more often you take it, the less the effect, and the stronger the craving for it. This is more or less how (this) addic…

From what I've heard, weed seems to work better after the first few tries.

In my personal experience, the opposite is true: the first times are the most intensive ones.

Re: How Cocaine Changes the Brain

#16

Post by ionised »

eru wrote: post #11
golergka wrote: post #6

Earlier quoted context omitted.

> So the first time(s) you use cocaine, you get a high that's incredible. The second time, this effect is about 100 times stronger than usual, so 10 times less strong than the first time. > Then you want to go back to that first unbelievable fantastic time, and take more. You may get at 200, but the more often you take it, the less the effect, and the stronger the craving for it. This is more or less how (this) addic…

From what I've heard, weed seems to work better after the first few tries.

That wasn't my experience when I used to smoke.

The first time I ever got stoned was the most effective.

Re: How Cocaine Changes the Brain

#17

Post by Nursie »

rogeryu wrote: post #5

Good to know is that the first time you take cocaine, it works about 1000 times stronger than the natural drugs in your brain, and thus the natural highs you get. These are the normal highs you get when you score a goal in sports, when you get an A for your exam, when the girl or boy you like wants to kiss you etc. So the first time(s) you use cocaine, you get a high that's incredible. The second time, this effect is…

I'm not sure it's quite that simple.

Diminishing returns from other drugs (MDMA for example) tend to prompt users to take a break for a while, so they can get the magic back later.

Re: How Cocaine Changes the Brain

#18

Post by DanBC »

golergka wrote: post #6
rogeryu wrote: post #5

Good to know is that the first time you take cocaine, it works about 1000 times stronger than the natural drugs in your brain, and thus the natural highs you get. These are the normal highs you get when you score a goal in sports, when you get an A for your exam, when the girl or boy you like wants to kiss you etc. So the first time(s) you use cocaine, you get a high that's incredible. The second time, this effect is…

> So the first time(s) you use cocaine, you get a high that's incredible. The second time, this effect is about 100 times stronger than usual, so 10 times less strong than the first time. > Then you want to go back to that first unbelievable fantastic time, and take more. You may get at 200, but the more often you take it, the less the effect, and the stronger the craving for it. This is more or less how (this) addic…

People who take heroin tend to desribe the vomiting of the first few tries, and of having to learn what the high is like.

But people using heroin develop a tolerance, and tolerance is part of the definition of a dependance.

Re: How Cocaine Changes the Brain

#19

Post by nugga »

From a harm reduction standpoint I wish they'd also research how long it takes until you return to baseline sensitivity or if at all. What is the approximate frequency and dose that you can take cocaine at where it's non destructive?

Re: How Cocaine Changes the Brain

#20

Post by mycroft-holmes »

eru wrote: post #11
golergka wrote: post #6

Earlier quoted context omitted.

> So the first time(s) you use cocaine, you get a high that's incredible. The second time, this effect is about 100 times stronger than usual, so 10 times less strong than the first time. > Then you want to go back to that first unbelievable fantastic time, and take more. You may get at 200, but the more often you take it, the less the effect, and the stronger the craving for it. This is more or less how (this) addic…

From what I've heard, weed seems to work better after the first few tries.

True for me
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