The most ridiculous part of Avatar was that the humans would give up and go home. More like they'd unleash some nukes and just take the unobtanium home.
I think chemical/biological warfare is MUCH more likely. "Unobtanium" can't get sick.
I agree totally. I wasn't putting too much thought into the actual method, I meant "nuke" in more of a colloquial "mass murder" sense.