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23andMe Wins a Second Life, Raises $115M

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11–20 of 118 posts

Re: 23andMe Wins a Second Life, Raises $115M

#11

This would make me anxious. I remember reading about someone who learned from 23andMe that they had a terminal disease or something like that, and it drastically altered their life. I'd rather just live in ignorance.

23andme user here (one of the first).

If the disease in question could be hard to handle mentally/emotionally, they specifically include a warning that is very direct and says "Are you sure you want to know this?".

Re: 23andMe Wins a Second Life, Raises $115M

#12

This would make me anxious. I remember reading about someone who learned from 23andMe that they had a terminal disease or something like that, and it drastically altered their life. I'd rather just live in ignorance.

wouldn't you rather make necessary arrangements and preparations for your family w that knowledge?

edit: i don't mean this as a criticism, genuine curiosity.

Re: 23andMe Wins a Second Life, Raises $115M

#13
post #6
post #3

I was so excited when 23andMe dropped their prices to $99 a few years ago and immediately gave myself a 'Christmas Present' and bought a 23andMe kit. I seriously thought this was the future. I was so excited to see my health information. It was really cool to see that my spit could confirm that I'm 1/2 asian and 1/2 european. Also, I found it interesting that I have more neanderthal DNA than 99% of people who took th…

Other than that, all the things I've seen are marginally useful at best. Part of it is that the FDA successfully sued 23AM from showing things like health risks.

The FDA put a stop to crowd-DNA research via the 23AM law suit. Prior to the lawsuit 23AM had a large user base completing questionnaires effectively mapping health risks, traits and allergies to genes. Not sure what the Food and Drug administration has to do with my genes other than regulatory overreach.

Re: 23andMe Wins a Second Life, Raises $115M

#14
post #9
post #6

Earlier quoted context omitted.

Other than that, all the things I've seen are marginally useful at best. Part of it is that the FDA successfully sued 23AM from showing things like health risks.

I still see the health risks, like to heart disease, cancer, etc. Might be because I'm grandfathered in?

Correct.

Re: 23andMe Wins a Second Life, Raises $115M

#15
post #6
post #3

I was so excited when 23andMe dropped their prices to $99 a few years ago and immediately gave myself a 'Christmas Present' and bought a 23andMe kit. I seriously thought this was the future. I was so excited to see my health information. It was really cool to see that my spit could confirm that I'm 1/2 asian and 1/2 european. Also, I found it interesting that I have more neanderthal DNA than 99% of people who took th…

Other than that, all the things I've seen are marginally useful at best. Part of it is that the FDA successfully sued 23AM from showing things like health risks.

That's not correct. The FDA made them stop doing something they were doing illegally. Their genetic test is a medical device and they didn't have federal approval.

Further, when the FDA informed them they needed approval, they didn't respond. The FDA finally had to invoke the law.

Also, I don't think 23&Me's test results have enough medical value to be used for evaluating health risks.

Further, 23&me's database has serious problems; for exmaple, they still report tongue rolling as a Mendelian trait. That alone shows that they aren't being careful with their analysis.

Re: 23andMe Wins a Second Life, Raises $115M

#16
post #6

Earlier quoted context omitted.

Other than that, all the things I've seen are marginally useful at best. Part of it is that the FDA successfully sued 23AM from showing things like health risks.

The FDA put a stop to crowd-DNA research via the 23AM law suit. Prior to the lawsuit 23AM had a large user base completing questionnaires effectively mapping health risks, traits and allergies to genes. Not sure what the Food and Drug administration has to do with my genes other than regulatory overreach.

This is not correct. They put a stop to 23&Me. There is still plenty of crowd-DNA research going on; for example, my genome and some medical information is online via GCG.

Re: 23andMe Wins a Second Life, Raises $115M

#17
post #6

Earlier quoted context omitted.

Other than that, all the things I've seen are marginally useful at best. Part of it is that the FDA successfully sued 23AM from showing things like health risks.

The FDA put a stop to crowd-DNA research via the 23AM law suit. Prior to the lawsuit 23AM had a large user base completing questionnaires effectively mapping health risks, traits and allergies to genes. Not sure what the Food and Drug administration has to do with my genes other than regulatory overreach.

They claimed it was a medical device in the same way as a glucose meter.

Re: 23andMe Wins a Second Life, Raises $115M

#18
post #6

Earlier quoted context omitted.

Other than that, all the things I've seen are marginally useful at best. Part of it is that the FDA successfully sued 23AM from showing things like health risks.

You can always export your raw data from 23andMe and plug it into third party (and I guess foreign) services that will give you some health info. Of course you should probably approach the results with some skepticism. I know someone who found out she had a gene that causes an early and very aggressive cancer and now can take pre-emptive measures that quite likely will save her life.

> I know someone who found out she had a gene that causes an early and very aggressive cancer and now can take pre-emptive measures that quite likely will save her life.

Do you mind if I ask what service she used for this?

Re: 23andMe Wins a Second Life, Raises $115M

#19

This would make me anxious. I remember reading about someone who learned from 23andMe that they had a terminal disease or something like that, and it drastically altered their life. I'd rather just live in ignorance.

wouldn't you rather make necessary arrangements and preparations for your family w that knowledge? edit: i don't mean this as a criticism, genuine curiosity.

I think it's an incredibly personal decision that you don't really have a place to criticize. I happen to agree with with that post as well, as long as it's not communicable, I'd 100% prefer not to know if I had a disease that was going to kill me.

If you're in a position to be responsible for others, shouldn't you already have a safety net/final arrangements? Diseases aren't the only things that can kill you unexpectedly, and even without a family I have life insurance, a living will, and all my other arrangements made.

Re: 23andMe Wins a Second Life, Raises $115M

#20
post #6

Earlier quoted context omitted.

Other than that, all the things I've seen are marginally useful at best. Part of it is that the FDA successfully sued 23AM from showing things like health risks.

The FDA put a stop to crowd-DNA research via the 23AM law suit. Prior to the lawsuit 23AM had a large user base completing questionnaires effectively mapping health risks, traits and allergies to genes. Not sure what the Food and Drug administration has to do with my genes other than regulatory overreach.

It has to do with the FDA protecting the public from crappy medical devices and drugs.

IF you want to sell a genetic test, you need to prove to the FDA: (1) that your test is accurate and reproducible, (2) that whatever conclusion you draw from the test is scientifically sound.

The issue was that 23&Me was saying "you have this SNP, that means your risk of X is increased by Y%". The test, the result and the conclusion is not based on a rigorous testing. Hell, some of the risk associated with SNPs is coincidental at best.

That said, I'm fine if people want that info anyways, but 23&Me would need to add a disclaimer that says "Your genetic test results and the risks attributed to them may or may not be accurate."

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