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Is Diet-Induced Alzheimer’s Disease Type 3 Diabetes?

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Re: Is Diet-Induced Alzheimer’s Disease Type 3 Diabetes?

#21

Post by michaelpinto »

linkydinkandyou wrote: post #16

We need to start holding people accountable for self-induced disease. Perhaps with taxes: tax the obese. However, even the people who think that "Alzheimer's" is "Type-3" diabetes don't believe that all senile dementia is "Type 3 Diabetes" or is diet-induced. Just certain types of it. But being obese is so unhealthy, and so easy to control (just eat LESS) that to not hold people accountable for it is not good or just…

Genetics plays a role in obesity:

https://en.wikipedia.org/wiki/Genetics_of_obesity

You can also be thin and have a bad diet, and while you may not be obese your internal systems can still be suffering from damage over the long run.

Something that should be noted: Many folks who are poor don't have access to high quality foods. So they can buy soda but not a salad. And what determines what makes those foods cheap or expensive are often driven by industry lobbying. So much so that when there was attempt to tax soda in NYC there was a great deal of money spent to stop that from going into effect.

Re: Is Diet-Induced Alzheimer’s Disease Type 3 Diabetes?

#22

Post by atomical »

rhinoceraptor wrote: post #5
0xcde4c3db wrote: post #2

Is diet-induced (or even diet-associated) Alzheimer's Disease a proven phenomenon in the first place? The article seems to be pretty speculative on the whole thing, and I'm under the impression that the research on lifestyle risk factors is quite inconclusive (e.g. risk factors show up in ecological studies but produce no significant difference in controlled intervention trials).

There is evidence of the neuroprotective effects of a ketogenic diet (low carb, moderate protein, very high fat) [1][2]. The original formulation of the ketogenic diet was for epilepsy, after all [3]. The dogma for decades has been that the brain needs glucose to function. A highly simplified and inaccurate explanation of Alzheimer's is that the brain has diminished capacity to use glucose. Luckily, the body has an a…

Actually, the problem is that keto diets are usually high in saturated fat. That increases the risk of heart disease.

Re: Is Diet-Induced Alzheimer’s Disease Type 3 Diabetes?

#23

Post by linkydinkandyou »

michaelpinto wrote: post #21
linkydinkandyou wrote: post #16

We need to start holding people accountable for self-induced disease. Perhaps with taxes: tax the obese. However, even the people who think that "Alzheimer's" is "Type-3" diabetes don't believe that all senile dementia is "Type 3 Diabetes" or is diet-induced. Just certain types of it. But being obese is so unhealthy, and so easy to control (just eat LESS) that to not hold people accountable for it is not good or just…

Genetics plays a role in obesity: https://en.wikipedia.org/wiki/Genetics_of_obesity You can also be thin and have a bad diet, and while you may not be obese your internal systems can still be suffering from damage over the long run. Something that should be noted: Many folks who are poor don't have access to high quality foods. So they can buy soda but not a salad. And what determines what makes those foods cheap or…

You can buy water for even less than a soda.

Here's what the left-leaning NPR says about Food Deserts and poor people's access to food.

http://www.npr.org/2010/12/15/132076786/the-root-the-myth-of...

And here's the NY Times http://www.nytimes.com/2012/04/18/health/research/pairing-of...

And here's the progressive magazine Slate:

http://www.slate.com/articles/life/food/2014/02/food_deserts...

Re: Is Diet-Induced Alzheimer’s Disease Type 3 Diabetes?

#24

Post by mobiuscog »

atomical wrote: post #22
rhinoceraptor wrote: post #5

Earlier quoted context omitted.

There is evidence of the neuroprotective effects of a ketogenic diet (low carb, moderate protein, very high fat) [1][2]. The original formulation of the ketogenic diet was for epilepsy, after all [3]. The dogma for decades has been that the brain needs glucose to function. A highly simplified and inaccurate explanation of Alzheimer's is that the brain has diminished capacity to use glucose. Luckily, the body has an a…

Actually, the problem is that keto diets are usually high in saturated fat. That increases the risk of heart disease.

Are we really still stuck on the saturated fat being 'evil' thing ? Even the mainstream guidelines are backing down on this now.

Re: Is Diet-Induced Alzheimer’s Disease Type 3 Diabetes?

#25

Post by atomical »

mobiuscog wrote: post #24
atomical wrote: post #22

Earlier quoted context omitted.

Actually, the problem is that keto diets are usually high in saturated fat. That increases the risk of heart disease.

Are we really still stuck on the saturated fat being 'evil' thing ? Even the mainstream guidelines are backing down on this now.

Which mainstream guidelines are you referring to?

Re: Is Diet-Induced Alzheimer’s Disease Type 3 Diabetes?

#26

Post by DanBC »

mobiuscog wrote: post #24
atomical wrote: post #22

Earlier quoted context omitted.

Actually, the problem is that keto diets are usually high in saturated fat. That increases the risk of heart disease.

Are we really still stuck on the saturated fat being 'evil' thing ? Even the mainstream guidelines are backing down on this now.

https://publichealthmatters.blog.gov.uk/2015/10/09/do-you-kn...

No, mainstream advice is still to control the amount of saturated fat you eat. This advice has remained the same for a while now. It hasn't changed. Shitty newspaper reporting makes people think it's changed.

Re: Is Diet-Induced Alzheimer’s Disease Type 3 Diabetes?

#27

Post by austinjp »

gavazzy wrote: post #8
rhinoceraptor wrote: post #5

Earlier quoted context omitted.

There is evidence of the neuroprotective effects of a ketogenic diet (low carb, moderate protein, very high fat) [1][2]. The original formulation of the ketogenic diet was for epilepsy, after all [3]. The dogma for decades has been that the brain needs glucose to function. A highly simplified and inaccurate explanation of Alzheimer's is that the brain has diminished capacity to use glucose. Luckily, the body has an a…

Blindly encouraging a ketogenic diet can actually be damaging. While the average person slightly benefits from a high-fat, low-carb diet, a small group of people (who have the APOE4 allele) are unable to properly digest fat and thus are greatly harmed by it. Similarly, light alcohol consumption seems to slightly benefit the majority of people. But, for those with APOE4, it causes significant harm. So, tonic for one g…

I'd be very interested to see specific references for this. I'll have a look for myself later, but if you have some to hand, that would be much appreciated.

Re: Is Diet-Induced Alzheimer’s Disease Type 3 Diabetes?

#28

Post by rhinoceraptor »

atomical wrote: post #25
mobiuscog wrote: post #24

Earlier quoted context omitted.

Are we really still stuck on the saturated fat being 'evil' thing ? Even the mainstream guidelines are backing down on this now.

Which mainstream guidelines are you referring to?

This is called the lipid hypothesis, you could say it has 'shaky' relationship with the truth. A shining example of the quote, "science advances one funeral at a time".

"Current evidence does not clearly support cardiovascular guidelines that encourage high consumption of polyunsaturated fatty acids and low consumption of total saturated fats." [1]

This myth has caused untold millions to die from western diseases, billions of wasted dollars on health care, and yet it still lives on. The future won't shine a good light on this era of nutrition.

[1]: http://annals.org/article.aspx?articleid=1846638

Re: Is Diet-Induced Alzheimer’s Disease Type 3 Diabetes?

#29

Post by gavazzy »

gavazzy wrote: post #17
einarvollset wrote: post #11

Earlier quoted context omitted.

You seem to have those the exact wrong way around, or? I have never heard any evidence that people with APOE mutations are "greatly harmed" by eating a ketogenic diet. Link? Ditto for alcohol.

My original post is correct. APOE 4/4 is sensitive to dietary fat; high fat diets cause large LDL [0]. Further, fat causes atherosclerosis in APOE 4/4 individuals more quickly than others [1]. It would make sense that APOE 4/4 would have this effect, because it is the "defective" form of APOE. Individuals with APOE 4/4 do not clear oxidized fats from the brain as quickly as APOE 2 or 3 individuals. [0] http://jn.nutr…

Update to previous post:

A study on diet and APOE genotype showed that fat content affects APOE 4 and APOE 2 or 3 people differently.

"No diet can be recommended unequivocally without knowing more about those being targeted. Even though a MUFA-rich diet increases LDL size compared with a CHO-rich diet, this effect is dependent on apoE genotypes. Thus, the replacement of a CHO diet by a MUFA diet increases LDL-size in apoE 3/3, whereas it decreases it in apoE 4/3 subjects"

http://jn.nutrition.org/content/134/10/2517.full.pdf+html

Re: Is Diet-Induced Alzheimer’s Disease Type 3 Diabetes?

#30

Post by atomical »

rhinoceraptor wrote: post #28
atomical wrote: post #25

Earlier quoted context omitted.

Which mainstream guidelines are you referring to?

This is called the lipid hypothesis, you could say it has 'shaky' relationship with the truth. A shining example of the quote, "science advances one funeral at a time". "Current evidence does not clearly support cardiovascular guidelines that encourage high consumption of polyunsaturated fatty acids and low consumption of total saturated fats." [1] This myth has caused untold millions to die from western diseases, bi…

Do you have the PDF?
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