The biggest challenge will the same thing that killed Concorde: finding customers to pay super prices for super speed.
Yet interestingly you can buy a Ferrari which goes more or less 2x as fast as, say, a VW Golf GTI and costs 10x the price, and there is burgeoning demand for the former. So if those economics apply in the air as well (speed = luxury / exclusivity), we should be able to sell cross-atlantic tickets for somewhere between 10 and 20x the price of a midrange air ticket which I would suggest is premium economy. So we're tal…
OTOH a Ferrari is a conspicuous sign of wealth and bad taste... the hypersonic flight, while significantly time-saving and maybe good for a couple of selfies on instagram, probably doesn't function so well in that regard