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Newly Risen from Yeast: THC

nytimes.com

11–20 of 63 posts

Re: Newly Risen from Yeast: THC

#11

Earlier quoted context omitted.

Scalable? Yes. Patentable? No. Although, the yeast could be a trade secret.

Monsanto holds patents on plant seeds. Why would yeast differ?

Could be that the patent would have to be on inserting genes in yeast generally, which isn't new.

Re: Newly Risen from Yeast: THC

#12

> European regulators, he said, are eager for a way to create a steady supply of THC and other cannabinoids without actually cultivating marijuana. “They are in fear that these plants will be grown and will support some illegal farming,” So the regulators are eager to flood the market with GMO THC, so they can stop people from growing their own organic THC? Sounds like they just want to commercialize & control it.

Except that marijuana seeds are effectively legal throughout the EU as long as they're not cultivated (ha).

If they really wanted to commercialize and control the sale of marijuana, they would legalize it.

Re: Newly Risen from Yeast: THC

#15
I have a strong dislike for these artificial THC drug pushes, because they ignore the real issue: the fact that marijuana helps people with a variety of medical ailments is largely because of the over 400+ cannabinoids, of which THC-cb1 and THC-cb2 are only two, while we are ignoring the other ones individually and as a compound/complementary effect.

For example, I know vets with PTSD who say mj is the only thing that helps them, but some of them are in states where the VA will stop providing care or withhold medication/treatment/payments if they test positive... but the VA has a deal with some pharmaceutical companies and it's legal to give two variations of synthetic THC, and every single one of the guys I know who have tried it have said it was nothing like mj, provided almost none of the benefits, and was often a very negative experience.

Don't misunderstand, I worked in biotech for a while and encourage the learning process of using methods like this to potentially produce and study certain drugs, but this is a drug that doesn't have a supply problem, because it's everywhere, it's easy to grow, it only has a legal problem. Synthetics seem like a way to capitalize legally on a black market that shouldn't exist.

Re: Newly Risen from Yeast: THC

#17
post #2

I don't see how this is superior to having the plant itself create THC which is much simpler and cheaper. Other than being a cool trick, how is this going to change the world, as the article claims? It really doesn't specify how the THC produced from yeast is any better or different than that produced from the plant. Can yeast production be scaled up in ways that plat production can't? Or is it just that it might be…

I had the same reaction -- what's the practical value here that makes it news?

One possible clue is in this quote: "[Cannabidiol] production from plants is a bit complicated." This might turn out to be by far the best way to obtain pure cannabidiol (and other cannabinoids).

I suspect that the long-term goal is to demonstrate new chemical synthesis techniques of interest to the pharmaceutical industry. The choice of THC (& hydrocodone) as an endpoint might have been somewhat arbitrary.

Re: Newly Risen from Yeast: THC

#18
post #11

Earlier quoted context omitted.

Monsanto holds patents on plant seeds. Why would yeast differ?

Could be that the patent would have to be on inserting genes in yeast generally, which isn't new.

Never underestimate the power of creative lawyering.

Re: Newly Risen from Yeast: THC

#19

> European regulators, he said, are eager for a way to create a steady supply of THC and other cannabinoids without actually cultivating marijuana. “They are in fear that these plants will be grown and will support some illegal farming,” So the regulators are eager to flood the market with GMO THC, so they can stop people from growing their own organic THC? Sounds like they just want to commercialize & control it.

> GMO THC

Well that's a new one, because THC isn't an "organism", nor is it "genetically modified".

Re: Newly Risen from Yeast: THC

#20

I have a strong dislike for these artificial THC drug pushes, because they ignore the real issue: the fact that marijuana helps people with a variety of medical ailments is largely because of the over 400+ cannabinoids, of which THC-cb1 and THC-cb2 are only two, while we are ignoring the other ones individually and as a compound/complementary effect. For example, I know vets with PTSD who say mj is the only thing tha…

This is exactly why I have an issue with meal replacement (e.g. soylent) stuff being used in the long term, or reductionistic nutrition advice that considers food only as a source of protein, carbs, fat and fiber. The fact is, we're discovering a ton of compounds in a ton of foods that have unexpected effects and benefits, not to mention synergistic effects that happen only when multiple compounds are together. To pretend that we know how all of it works seems like hubris to me.
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